Overview of nanoparticulate strategies for solubility enhancement of poorly soluble drugs

KU Khan, MU Minhas, SF Badshah, M Suhail, A Ahmad… - Life Sciences, 2022 - Elsevier
Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …

Therapeutic deep eutectic solvents: A comprehensive review of their thermodynamics, microstructure and drug delivery applications

MM Abdelquader, S Li, GP Andrews… - European Journal of …, 2023 - Elsevier
Deep eutectic solvents (DES) are multicomponent liquids that are usually formed by
coupling a hydrogen bond donor and acceptor leading to strong non-covalent (NC) …

[图书][B] Handbook of pharmaceutical excipients

RC Rowe, P Sheskey, M Quinn - 2009 - repositorio.ub.edu.ar
Pharmaceutical dosage forms contain both pharmacologically active compounds and
excipients added to aid the formulation and manufacture of the subsequent dosage form for …

Polysaccharide-based aerogels—Promising biodegradable carriers for drug delivery systems

CA García-González, M Alnaief, I Smirnova - Carbohydrate polymers, 2011 - Elsevier
Polysaccharides are regarded as key ingredients for the production of bio-based materials
in life sciences (eg, food, cosmetics, medical devices, pharmaceutics). The biodegradability …

[图书][B] The Royal Marsden manual of clinical nursing procedures

L Dougherty, S Lister - 2015 - books.google.com
Nationally recognised as the definitive guide to clinical nursing skills, The Royal Marsden
Manual of Clinical Nursing Procedures has provided essential nursing knowledge and up-to …

Soluplus®: a novel polymeric solubilizer for optimization of carvedilol solid dispersions: formulation design and effect of method of preparation

RN Shamma, M Basha - Powder technology, 2013 - Elsevier
The aim of this work was to investigate the applicability of different industrially scalable
techniques in the preparation of solid dispersions using a novel polyvinyl caprolactam …

Status of surfactants as penetration enhancers in transdermal drug delivery

I Som, K Bhatia, M Yasir - Journal of pharmacy and bioallied …, 2012 - journals.lww.com
Surfactants are found in many existing therapeutic, cosmetic, and agro-chemical
preparations. In recent years, surfactants have been employed to enhance the permeation …

[PDF][PDF] TRANSDERMAL DRUG DELIVERY SYSTEM: A REVIEW.

AV Patel, BN Shah - Pharma Science Monitor, 2018 - pharmasm.com
The administration of drugs by transdermal route offers the advantage of being relatively
painless. The appeal of using the skin as a portal of drug entry lies in case of access, its …

Microfluidic and lab-on-a-chip preparation routes for organic nanoparticles and vesicular systems for nanomedicine applications

L Capretto, D Carugo, S Mazzitelli, C Nastruzzi… - Advanced drug delivery …, 2013 - Elsevier
In recent years, advancements in the fields of microfluidic and lab-on-a-chip technologies
have provided unique opportunities for the implementation of nanomaterial production …

Strategies for formulating and delivering poorly water-soluble drugs

M Rodriguez-Aller, D Guillarme, JL Veuthey… - Journal of Drug Delivery …, 2015 - Elsevier
Water solubility is a key parameter in drug formulation since it highly influences drug
pharmacokinetics and pharmacodynamics. In the past decades, the challenge with poorly …