Population genetic models for the spatial spread of adaptive variants: A review in light of SARS-CoV-2 evolution

MC Steiner, J Novembre - PLoS Genetics, 2022 - journals.plos.org
Theoretical population genetics has long studied the arrival and geographic spread of
adaptive variants through the analysis of mathematical models of dispersal and natural …

slendr: a framework for spatio-temporal population genomic simulations on geographic landscapes

M Petr, BC Haller, PL Ralph… - Peer Community …, 2023 - peercommunityjournal.org
One of the goals of population genetics is to understand how evolutionary forces shape
patterns of genetic variation over time. However, because populations evolve across both …

[HTML][HTML] Resource-explicit interactions in spatial population models

SE Champer, B Chae, BC Haller, J Champer… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Continuous-space population models can yield significantly different results from their
panmictic counterparts when assessing evolutionary, ecological, or population-genetic …

Exploring the effects of ecological parameters on the spatial structure of genetic tree sequences

MK Ianni-Ravn, M Petr… - Peer Community …, 2024 - peercommunityjournal.org
Geographic space is a fundamental dimension of evolutionary change, determining how
individuals disperse and interact with each other. Consequently, space has an important …

[HTML][HTML] Analyses of allele age and fitness impact reveal human beneficial alleles to be older than neutral controls

AM Pivirotto, A Platt, R Patel, S Kumar, J Hey - bioRxiv, 2023 - ncbi.nlm.nih.gov
A classic population genetic prediction is that alleles experiencing directional selection
should swiftly traverse allele frequency space, leaving detectable reductions in genetic …

Analyses of allele age and fitness impact reveal human beneficial alleles to be older than neutral controls

AM Pivirotto, A Platt, R Patel, S Kumar, J Hey - bioRxiv, 2023 - biorxiv.org
A classic population genetic prediction is that alleles experiencing directional selection
should swiftly traverse allele frequency space, leaving detectable reductions in genetic …

Dynamics of Natural Selection on Human Genomic Variants

AM Pivirotto - 2024 - search.proquest.com
Evolutionary adaptation in humans is shaped primarily by the selection of beneficial alleles.
Classical population genetic theory predicts that alleles under selection will experience a …

The Palaeogenomics of Arctic and Sub-Arctic Peoples: A Study of Population Genetics, Adaptations, and Pathogen Incidence

A Sutherland - 2023 - repository.cam.ac.uk
The northeastern regions of Siberia and the North American Arctic are some of the last
regions of the world to be inhabited by humans; there, sophisticated technologies were …

[PDF][PDF] Peer Community Journal

M Petr, BC Haller, PL Ralph, F Racimo - benhaller.com
One of the goals of population genetics is to understand how evolutionary forces shape
patterns of genetic variation over time. However, because populations evolve across both …