A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single
molecule are basically designed to interact with multiple targets or to amplify its effect …

Heterocyclic compounds account for the most prominent and diverse class of organic
compounds. A significant number of heterocyclic compounds have been synthesized up to …

The biological activity of Mannich bases, a structurally heterogeneous class of chemical
compounds that are generated from various substrates through the introduction of an …

Abstract The 1, 3, 4‐oxadiazole nucleus is a biologically imperative scaffold possesses
numerous biological activities. The broad and potent activity of 1, 3, 4‐oxadiazole and their …

Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …

The synthetic strategies and characterization of some novel 1, 3, 4-oxadiazole derivatives
carrying different pharmacophores and heterocyclic rings that are relevant to potential …

Non-Steroidal biologically active heterocyclic compounds 4-(2-(4-chlorophenyl) benzo [d]
thiazol-3 (2H)-yl)-N-((3-substituted-2-hydrobenzo [d] thiazol-2-yl) methylene) thiazol-2 …

Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …

Abstract Five member heterocyclic 1, 3, 4-oxadiazole nucleus find unique place in medicinal
chemistry and plays significant role in producing anticancer activity. The small and simple 1 …

Twenty benzothiazole derivatives bearing a 1, 3, 4-oxadiazole moiety were synthesized and
evaluated for their anti-oxidant and anti-inflammatory activities. Among these compounds …