Peptide affinity chromatography applied to therapeutic antibodies purification

GR Barredo-Vacchelli, SL Giudicessi… - International Journal of …, 2021 - Springer
The interest in therapeutic monoclonal antibodies (mAbs) has significantly grown in the
pharmaceutical industry, exceeding 100 FDA mAbs approved. Although the upstream …

The downstream purification of bispecific antibodies

Q Li, H Zhao, X Liang, Q He, Z Wang, G Qin, GZ Li… - Analytical …, 2024 - Elsevier
Bispecific antibodies, a class of therapeutic antibodies, can simultaneously bind to two
distinct targets. Compared with monospecific antibodies, bispecific antibodies offer …

Biosensing materials for monoclonal antibody detection: An overview

Y Zhang, F Fan, Y Chai, X Chen - Responsive Materials, 2024 - Wiley Online Library
Considering the continuous advances in the synthesis and clinical applications of
monoclonal antibodies (mAbs), precision therapies that employ mAbs are essential. In …

Evaluation of hydrophobic charge-induction ligand efficiency for protein adsorption in one single cycle

W Shi, X Zhang, X Kong, J Fu, S Zhang, K Li… - … of Chromatography A, 2022 - Elsevier
Ligand is an essential part of the cost of adsorbent preparation, which needs to be carefully
selected and evaluated. In this paper, we introduced ligand efficiency (L e) with three levels …

[HTML][HTML] Protocol for bevacizumab purification using Ac-PHQGQHIGVSK-agarose

GR Barredo, SL Giudicessi, MCM Ceron, SL Saavedra… - MethodsX, 2020 - Elsevier
Bevacizumab is a monoclonal antibody, produced in CHO cells, used for the treatment of
many human cancers. It is an anti-vascular endothelial growth factor (antsi-VEGF) that …

Green solvents in the biotechnology-based pharmaceutical industry

SL Giudicessi, SL Saavedra, AB Cardillo… - … Sustainable Process for …, 2021 - Elsevier
Abstract After the Industrial Revolution, humanity began to exploit nonrenewable resources,
such as oil and gas, with dangerous consequences for the environment. In the last 50 years …

[PDF][PDF] Magnetic Affinity Nanoparticles for Bevacizumab Adsorption

GR Barredo-Vacchelli, SL Giudicessi, F Albericio… - kvinzo.com
The vascular endothelial growth factor (VEGF) stimulates tumor angiogenesis by targeting
its receptor (VEGFR)[1]. The IgG monoclonal antibody bevacizumab, produced in CHO cells …

Peptide Affinity Chromatography Applied to Therapeutic Antibodies Purification

GR Barredo, SL Giudicessi, MC Martínez Ceron… - 2021 - ri.conicet.gov.ar
The interest in therapeutic monoclonal antibodies (mAbs) has significantly grown in the
pharmaceutical industry, exceeding 100 FDA mAbs approved. Although the upstream …

Green solvents in the biotechnology-based pharmaceutical industry

OS Casconea, L Saavedraa… - … for Chemical and …, 2020 - books.google.com
Until the 18th century (Fig. 1), humanity used practically only renewable resources to meet
our daily needs such as food, clothing, and housing. However, in the 19th and 20th …