Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin …

CA Bousman, JM Stevenson… - Clinical …, 2023 - Wiley Online Library
Serotonin reuptake inhibitor antidepressants, including selective serotonin reuptake
inhibitors (SSRIs; ie, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and …

Candidate biomarkers in psychiatric disorders: state of the field

A Abi‐Dargham, SJ Moeller, F Ali… - World …, 2023 - Wiley Online Library
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

Treatment selection in depression

ZD Cohen, RJ DeRubeis - Annual Review of Clinical …, 2018 - annualreviews.org
Mental health researchers and clinicians have long sought answers to the question “What
works for whom?” The goal of precision medicine is to provide evidence-based answers to …

World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of unipolar depressive disorders, part 1: update 2013 on the acute …

M Bauer, A Pfennig, E Severus… - The world journal of …, 2013 - Taylor & Francis
Objectives. This 2013 update of the practice guidelines for the biological treatment of
unipolar depressive disorders was developed by an international Task Force of the World …

An inflammatory biomarker as a differential predictor of outcome of depression treatment with escitalopram and nortriptyline

R Uher, KE Tansey, T Dew, W Maier… - American Journal of …, 2014 - Am Psychiatric Assoc
Objective: Major depressive disorder has been linked with inflammatory processes, but it is
unclear whether individual differences in levels of inflammatory biomarkers could help …

Linking molecules to mood: new insight into the biology of depression

V Krishnan, EJ Nestler - American Journal of Psychiatry, 2010 - Am Psychiatric Assoc
Major depressive disorder is a heritable psychiatric syndrome that appears to be associated
with subtle cellular and molecular alterations in a complex neural network. The affected …

Candidate genes expression profile associated with antidepressants response in the GENDEP study: differentiating between baseline 'predictors' and longitudinal ' …

A Cattaneo, M Gennarelli, R Uher, G Breen… - …, 2013 - nature.com
To improve the 'personalized-medicine'approach to the treatment of depression, we need to
identify biomarkers that, assessed before starting treatment, predict future response to …

Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2008 British Association for Psychopharmacology guidelines

A Cleare, CM Pariante, AH Young… - Journal of …, 2015 - journals.sagepub.com
A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

Establishing moderators and biosignatures of antidepressant response in clinical care (EMBARC): Rationale and design

MH Trivedi, PJ McGrath, M Fava, RV Parsey… - Journal of psychiatric …, 2016 - Elsevier
Abstract Remission rates for Major Depressive Disorder (MDD) are low and unpredictable
for any given antidepressant. No biological or clinical marker has demonstrated sufficient …

Overview of the genetics of major depressive disorder

FW Lohoff - Current psychiatry reports, 2010 - Springer
Major depressive disorder (MDD) is a common psychiatric illness with high levels of
morbidity and mortality. Despite intensive research during the past several decades, the …