The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can aid in objectively diagnosing patients and providing individualized treatment …
Mental health researchers and clinicians have long sought answers to the question “What works for whom?” The goal of precision medicine is to provide evidence-based answers to …
Objectives. This 2013 update of the practice guidelines for the biological treatment of unipolar depressive disorders was developed by an international Task Force of the World …
R Uher, KE Tansey, T Dew, W Maier… - American Journal of …, 2014 - Am Psychiatric Assoc
Objective: Major depressive disorder has been linked with inflammatory processes, but it is unclear whether individual differences in levels of inflammatory biomarkers could help …
V Krishnan, EJ Nestler - American Journal of Psychiatry, 2010 - Am Psychiatric Assoc
Major depressive disorder is a heritable psychiatric syndrome that appears to be associated with subtle cellular and molecular alterations in a complex neural network. The affected …
To improve the 'personalized-medicine'approach to the treatment of depression, we need to identify biomarkers that, assessed before starting treatment, predict future response to …
A revision of the 2008 British Association for Psychopharmacology evidence-based guidelines for treating depressive disorders with antidepressants was undertaken in order to …
MH Trivedi, PJ McGrath, M Fava, RV Parsey… - Journal of psychiatric …, 2016 - Elsevier
Abstract Remission rates for Major Depressive Disorder (MDD) are low and unpredictable for any given antidepressant. No biological or clinical marker has demonstrated sufficient …
FW Lohoff - Current psychiatry reports, 2010 - Springer
Major depressive disorder (MDD) is a common psychiatric illness with high levels of morbidity and mortality. Despite intensive research during the past several decades, the …