Radiopharmaceuticals for PET and SPECT imaging: a literature review over the last decade

G Crișan, NS Moldovean-Cioroianu… - International journal of …, 2022 - mdpi.com
Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Review on 99mTc radiopharmaceuticals with emphasis on new advancements

A Duatti - Nuclear medicine and biology, 2021 - Elsevier
Rapid imaging acquisition, high spatial resolution and sensitivity, powered by
advancements in solid-state detector technology, are significantly changing the perspective …

Overview of radiolabeled somatostatin analogs for cancer imaging and therapy

R Eychenne, C Bouvry, M Bourgeois, P Loyer… - Molecules, 2020 - mdpi.com
Identified in 1973, somatostatin (SST) is a cyclic hormone peptide with a short biological half-
life. Somatostatin receptors (SSTRs) are widely expressed in the whole body, with five …

Technetium (I) carbonyl complexes for nuclear medicine: Coordination-chemical aspect

GV Sidorenko, AE Miroslavov, MY Tyupina - Coordination Chemistry …, 2023 - Elsevier
Studies concerning the development of radiopharmaceuticals based on the Tc (I) carbonyl
core are considered from the coordination-chemical viewpoint. The coordination behavior of …

Bifunctional chelators for radiorhenium: Past, present and future outlook

DR Melis, AR Burgoyne, M Ooms… - RSC Medicinal Chemistry, 2022 - pubs.rsc.org
Targeted radionuclide therapy (TRNT) is an ever-expanding field of nuclear medicine that
provides a personalised approach to cancer treatment while limiting toxicity to normal …

1,4,7-Triazacyclononane-Based Chelators for the Complexation of [186Re]Re- and [99mTc]Tc-Tricarbonyl Cores

R Hoerres, HM Hennkens - Inorganic Chemistry, 2023 - ACS Publications
Metal complexes with the general formula [MI (CO) 3 (k3-L)]+, where M= Re, 186Re, or
99mTc and L= 1, 4, 7-triazacyclononane (TACN), NOTA, or NODAGA chelators, have …

[HTML][HTML] Bio-vehicles of cytotoxic drugs for delivery to tumor specific targets for cancer precision therapy

L Al-Mansoori, P Elsinga, SK Goda - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Abnormal structural and molecular changes in malignant tissues were thoroughly
investigated and utilized to target tumor cells, hence rescuing normal healthy tissues and …

Novel [99mTc]-Tricarbonyl-NOTA-Conjugated Lactam-Cyclized Alpha-MSH Peptide with Enhanced Melanoma Uptake and Reduced Renal Uptake

Z Qiao, J Xu, R Gonzalez, Y Miao - Molecular pharmaceutics, 2020 - ACS Publications
The purpose of this study was to examine the melanoma targeting and imaging properties of
99mTc (CO) 3-NOTA-GGNle-CycMSHhex {1, 4, 7-triazacyclononane-1, 4, 7-triyl-triacetic …

Development and Preclinical Evaluation of 99mTc- and 186Re-Labeled NOTA and NODAGA Bioconjugates Demonstrating Matched Pair Targeting of GRPR …

G Makris, RP Bandari, M Kuchuk, SS Jurisson… - Molecular Imaging and …, 2021 - Springer
Purpose The goal of this work was to develop hydrophilic gastrin-releasing peptide receptor
(GRPR)-targeting complexes of the general formula fac-[M (CO) 3 (L)]+[M= nat Re, 99m Tc …

DNA interaction studies of rhenium compounds with Schiff base chelates encompassing biologically relevant moieties

MB Ismail, IN Booysen, MP Akerman - … , Nucleotides and Nucleic …, 2019 - Taylor & Francis
Herein, we report the DNA interaction studies of rhenium (I) and-(V) compounds with Schiff
base chelates encompassing biologically relevant moieties. More specifically, the DNA …