Chronic wounds

V Falanga, RR Isseroff, AM Soulika… - Nature Reviews …, 2022 - nature.com
Chronic wounds are characterized by their inability to heal within an expected time frame
and have emerged as an increasingly important clinical problem over the past several …

The role of antioxidants on wound healing: A review of the current evidence

IM Comino-Sanz, MD López-Franco, B Castro… - Journal of clinical …, 2021 - mdpi.com
(1) Background: Reactive oxygen species (ROS) play a crucial role in the preparation of the
normal wound healing response. Therefore, a correct balance between low or high levels of …

Chronic wounds: Treatment consensus

E Eriksson, PY Liu, GS Schultz… - Wound repair and …, 2022 - Wiley Online Library
Abstract The Wound Healing Foundation (WHF) recognised a need for an unbiased
consensus on the best treatment of chronic wounds. A panel of 13 experts were invited to a …

Exosomes laden self-healing injectable hydrogel enhances diabetic wound healing via regulating macrophage polarization to accelerate angiogenesis

K Wang, R Dong, J Tang, H Li, J Dang, Z Zhang… - Chemical Engineering …, 2022 - Elsevier
Developing multifunctional wound dressings capable of inducing rapid angiogenesis
provides promise for diabetic wound healing, and triggering proper immune responses has …

Macrophage related chronic inflammation in non-healing wounds

M Li, Q Hou, L Zhong, Y Zhao, X Fu - Frontiers in Immunology, 2021 - frontiersin.org
Persistent hyper-inflammation is a distinguishing pathophysiological characteristic of chronic
wounds, and macrophage malfunction is considered as a major contributor thereof. In this …

Bioinspired conductive silk microfiber integrated bioelectronic for diagnosis and wound healing in diabetes

Z Jia, J Gong, Y Zeng, J Ran, J Liu… - Advanced Functional …, 2021 - Wiley Online Library
Ideal epidermal bioelectronics can be used not only for long‐term detection of physiological
signals for disease diagnosis but also for chronic disease treatment. Silk, an animal‐derived …

[HTML][HTML] Challenges in the treatment of chronic wounds

G FrykbergRobert - Advances in wound care, 2015 - liebertpub.com
Significance: Chronic wounds include, but are not limited, to diabetic foot ulcers, venous leg
ulcers, and pressure ulcers. They are a challenge to wound care professionals and …

Biofilms in diabetic foot ulcers: significance and clinical relevance

C Pouget, C Dunyach-Remy, A Pantel, S Schuldiner… - Microorganisms, 2020 - mdpi.com
Foot infections are the main disabling complication in patients with diabetes mellitus. These
infections can lead to lower-limb amputation, increasing mortality and decreasing the quality …

Cryogel/hydrogel biomaterials and acupuncture combined to promote diabetic skin wound healing through immunomodulation

TY Chen, TK Wen, NT Dai, S Hsu - Biomaterials, 2021 - Elsevier
Unhealed chronic wounds often deteriorate into multiple infection with several kinds of
bacteria and excessive proteolytic wound exudate and remains one of the common …

Antioxidant PLA composites containing lignin for 3D printing applications: a potential material for healthcare applications

J Domínguez-Robles, NK Martin, ML Fong, SA Stewart… - Pharmaceutics, 2019 - mdpi.com
Lignin (LIG) is a natural biopolymer with well-known antioxidant capabilities. Accordingly, in
the present work, a method to combine LIG with poly (lactic acid)(PLA) for fused filament …