The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications

Y Zhang, Z Zhang - Cellular & molecular immunology, 2020 - nature.com
Immunotherapy has revolutionized cancer treatment and rejuvenated the field of tumor
immunology. Several types of immunotherapy, including adoptive cell transfer (ACT) and …

Turning the corner on therapeutic cancer vaccines

RE Hollingsworth, K Jansen - npj Vaccines, 2019 - nature.com
Recent advances in several areas are rekindling interest and enabling progress in the
development of therapeutic cancer vaccines. These advances have been made in target …

The research progress of antiangiogenic therapy, immune therapy and tumor microenvironment

H Hu, Y Chen, S Tan, S Wu, Y Huang, S Fu… - Frontiers in …, 2022 - frontiersin.org
Anti-angiogenesis therapy, a promising strategy against cancer progression, is limited by
drug-resistance, which could be attributed to changes within the tumor microenvironment …

Cancer vaccines: toward the next breakthrough in cancer immunotherapy

Y Igarashi, T Sasada - Journal of immunology research, 2020 - Wiley Online Library
Until now, three types of well‐recognized cancer treatments have been developed, ie,
surgery, chemotherapy, and radiotherapy; these either remove or directly attack the cancer …

Therapeutic cancer vaccines: past, present, and future

C Guo, MH Manjili, JR Subjeck, D Sarkar… - Advances in cancer …, 2013 - Elsevier
Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim
to treat late stage disease by using a patient's own immune system. The promising results …

[HTML][HTML] Engineered tumor cell-derived vaccines against cancer: The art of combating poison with poison

X Zhang, H Cui, W Zhang, Z Li, J Gao - Bioactive Materials, 2023 - Elsevier
Tumor vaccination is a promising approach for tumor immunotherapy because it presents
high specificity and few side effects. However, tumor vaccines that contain only a single …

Cancer immunotherapy: moving beyond current vaccines

SA Rosenberg, JC Yang, NP Restifo - Nature medicine, 2004 - nature.com
Great progress has been made in the field of tumor immunology in the past decade, but
optimism about the clinical application of currently available cancer vaccine approaches is …

Cytokines in cancer pathogenesis and cancer therapy

G Dranoff - Nature Reviews Cancer, 2004 - nature.com
The mixture of cytokines that is produced in the tumour microenvironment has an important
role in cancer pathogenesis. Cytokines that are released in response to infection …

[HTML][HTML] Immunotherapy for colorectal cancer

S Koido, T Ohkusa, S Homma, Y Namiki… - World journal of …, 2013 - ncbi.nlm.nih.gov
The incidence of colorectal cancer (CRC) is on the rise, and the prognosis for patients with
recurrent or metastatic disease is extremely poor. Although chemotherapy and radiation …

Assessing the future of solid tumor immunotherapy

P Guha, KR Heatherton, KP O'Connell, IS Alexander… - Biomedicines, 2022 - mdpi.com
With the advent of cancer immunotherapy, there has been a major improvement in patient's
quality of life and survival. The growth of cancer immunotherapy has dramatically changed …