Tumour heterogeneity encompasses both the malignant cells and their microenvironment.
While heterogeneity between individual patients is known to affect the efficacy of cancer …

Flow cytometry (FC) has a well‐established role in the diagnostic evaluation of mature B‐
cell neoplasms. Effective assessment for lineage associated antigens, aberrant antigen …

The diagnosis of leukemic T-cell malignancies is often challenging, due to overlapping
features with reactive T-cells and limitations of currently available T-cell clonality assays …

Flow cytometry has been indispensable in diagnosing B cell lymphoma and plasma cell
neoplasms. The advances in novel multicolor flow cytometry have also made this technology …

Understanding tumor heterogeneity and immune infiltrates within the tumor-immune
microenvironment (TIME) is essential for the innovation of immunotherapies. Here …

Introduction Our previous studies have demonstrated that tumor-infiltrating lymphocytes
(TILs), including normal B cells, T cells, and natural killer (NK) cells, in diffuse large B-cell …

This third edition is the product of the author's 25 years of experience with flow cytometry;
although it covers the wide spectrum of hematopoietic tumors, the focus remains on most …

Background Follicular lymphoma (FL) is an indolent non‐Hodgkin lymphoma that has a risk
of transformation to more aggressive lymphoma. Relatively little is known about the …

Most non-Hodgkin's lymphomas grow exclusively in the lymph node compartment protected
by the tumor microenvironment. To better understand the cellular heterogeneity and the …

This atlas presents not only the differential diagnosis but also the detailed morphologic,
immunophenotypic, and especially genetic characteristics of the majority of hematolymphoid …