The role of nuclear factor erythroid 2-related factor 2 (NRF2) in arsenic toxicity

SR El-Mahrouk, MA El-Ghiaty, AOS El-Kadi - Journal of Environmental …, 2024 - Elsevier
Arsenic, a naturally occurring toxic element, manifests in various chemical forms and is
widespread in the environment. Exposure to arsenic is a well-established risk factor for an …

Risk assessment of small organoarsenic species in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2024 - Wiley Online Library
Abstract The European Commission asked EFSA for a risk assessment on small
organoarsenic species in food. For monomethylarsonic acid MMA (V), decreased body …

Dimethylmonothioarsinic acid (DMMTAV) differentially modulates the expression of AHR-regulated cytochrome P450 1A enzymes in vivo and in vitro

SR El-Mahrouk, MA El-Ghiaty, MA Alqahtani… - Toxicology Letters, 2024 - Elsevier
Dimethylmonothioarsinic acid (DMMTA V), a pentavalent thio-arsenic derivative, has been
found in bodily fluids and tissues including urine, liver, kidney homogenates, plasma, and …

Alteration of Hepatic Cytochrome P450 Expression and Arachidonic Acid Metabolism by Arsenic Trioxide (ATO) in C57BL/6 Mice

MA El-Ghiaty, MA Alqahtani, SR El-Mahrouk… - … Trace Element Research, 2024 - Springer
The success of arsenic trioxide (ATO) in acute promyelocytic leukemia has driven a plethora
studies to investigate its efficacy in other malignancies. However, the inherent toxicity of ATO …