Therapeutic potential of mesenchymal stem/stromal cells (MSCs)-based cell therapy for inflammatory bowel diseases (IBD) therapy

MJ Saadh, MV Mikhailova, S Rasoolzadegan… - European Journal of …, 2023 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) therapy has become an emerging
therapeutic modality for the treatment of inflammatory bowel disease (IBD), given their …

Multifaceted roles of chemokine CXC motif ligand 7 in inflammatory diseases and cancer

Q Wu, H Tu, J Li - Frontiers in Pharmacology, 2022 - frontiersin.org
Over recent years, CXC motif ligand 7 (CXCL7) has received widespread attention as a
chemokine involved in inflammatory responses. Abnormal production of the chemokine …

Network pharmacology analysis and experimental validation of kaempferol in the treatment of ischemic stroke by inhibiting apoptosis and regulating …

SS Zhang, M Liu, DN Liu, YF Shang, GH Du… - International Journal of …, 2022 - mdpi.com
Kaempferol, a natural plant flavonoid compound, has a neuroprotective effect on ischemic
stroke, while the specific mechanism remains unclear. In the current study, we applied the …

Ketogenesis alleviates TNFα-induced apoptosis and inflammatory responses in intestinal cells

JT Kim, DL Napier, J Kim, C Li, EY Lee… - Free Radical Biology …, 2021 - Elsevier
The disturbance of strictly regulated self-regeneration in mammalian intestinal epithelium is
associated with various intestinal disorders, particularly inflammatory bowel diseases (IBDs) …

CXCL6: A potential therapeutic target for inflammation and cancer

CL Dai, HX Yang, QP Liu, K Rahman… - Clinical and Experimental …, 2023 - Springer
Chemokines were originally defined as cytokines that affect the movement of immune cells.
In recent years, due to the increasing importance of immune cells in the tumor …

CXC chemokines as therapeutic targets and prognostic biomarkers in skin cutaneous melanoma microenvironment

X Zhou, M Peng, Y He, J Peng, X Zhang… - Frontiers in …, 2021 - frontiersin.org
Background Skin Cutaneous Melanoma (SKCM) is a tumor of the epidermal melanocytes
induced by gene activation or mutation. It is the result of the interaction between genetic …

Identification of diagnostic biomarks and immune cell infiltration in ulcerative colitis

Q Chen, S Bei, Z Zhang, X Wang, Y Zhu - Scientific Reports, 2023 - nature.com
We aimed to explore diagnostic biomarks and immune cell infiltration characteristics in
ulcerative colitis (UC). We used the dataset GSE38713 as the training set and dataset …

[HTML][HTML] Identification of novel population-specific cell subsets in Chinese ulcerative colitis patients using single-cell RNA sequencing

G Li, B Zhang, J Hao, X Chu, M Wiestler… - Cellular and molecular …, 2021 - Elsevier
Abstract Background & Aims Genome-wide association studies (GWAS) and transcriptome
analyses have been performed to better understand the pathogenesis of ulcerative colitis …

Vitex trifolia L. modulates inflammatory mediators via down-regulation of the NF-κB signaling pathway in carrageenan-induced acute inflammation in experimental rats

P Annamalai, EB Thangam - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Vitex trifolia L.(V. trifolia L.), commonly known as the three-
leaved chaste tree, is extensively employed in traditional Chinese medicine (TCM) to treat …

CXCL14 and miR-4484 serves as potential salivary biomarkers for early detection of peri-implantitis

G Urvasizoglu, A Kilic, O Capik, M Gundogdu… - Odontology, 2024 - Springer
Abstract Peri-implantitis develops in 43.3% of implant patients, which affects tissues around
the implant that may ultimately cause implant loss if not treated properly. Due to difficulties in …