It would not be practical to attempt to deal with all the advances that have informed our
understanding of the behavior and functions of this enzyme over the past 90 years. This …

Monoamine oxidase (MAO) inhibitors have made significant contributions and remain an
indispensable approach of molecular and mechanistic diversity for the discovery of …

Monoamine oxidases (MAO) are biocatalysts for the oxidation of a wide range of different
amines including α-chiral amines. Their high selectivity and activity, along with the …

The enzyme-catalyzed degradation of the biogenic amine serotonin is an essential
regulatory mechanism of its level in the human organism. In particular, monoamine oxidase …

Monoamine oxidases (MAOs) catalyse the oxidation of neurotransmitter amines and a wide
variety of primary, secondary and tertiary amine xenobiotics, including therapeutic drugs …

The flavoenzyme monoamine oxidase (MAO) regulates mammalian behavioral patterns by
modulating neurotransmitters such as adrenaline and serotonin. The mechanistic basis …

Monoamine oxidases (MAOs) A and B are flavoenzymes responsible for the metabolism of
biogenic amines such as dopamine, serotonin and noradrenaline. In this work, we present a …

Monoamine oxidases (MAO) A and B are important flavoenzymes involved in the
metabolism of amine neurotransmitters. Orru et al.(J. Neural Transm. 2013, 120, 847− 851) …

Two of the possible catalytic mechanisms for neurotransmitter oxidative deamination by
monoamine oxidase B (MAO B), namely, polar nucleophilic and hydride transfer, were …

HIGHLIGHTS Computational techniques provide accurate descriptions of the structure and
dynamics of biological systems, contributing to their understanding at an atomic level …