Over the years, in order to survive in their natural environment, microbial communities have
acquired adaptations to nonoptimal growth conditions. These shifts are usually related to …

Simple Summary Mycobacterium tuberculosis is a bacterium of great medical importance
because it causes tuberculosis, a disease that affects millions of people worldwide. Two …

Antimicrobial resistance genes (ARGs) and virulence factor genes (VFGs) constitute a
serious threat to public health, and climate change has been predicted to affect the increase …

Since the initial discovery of universal stress protein A (UspA) 25 years ago, remarkable
advances in molecular and biochemical technologies have revolutionized our …

We present the crystal structures of two universal stress proteins (USP) from A rchaeoglobus
fulgidus and N itrosomonas europaea in both apo‐and ligand‐bound forms. This work is the …

It is thought that during latent infection, Mycobacterium tuberculosis bacilli are retained
within granulomas in a low-oxygen environment. The dormancy survival (Dos) regulon …

Host redox dependent physiological responses play crucial roles in the determination of
mycobacterial infection process. Mtb explores oxygen rich lung microenvironments to initiate …

One-quarter of the world's population is infected with Mycobacterium tuberculosis (Mtb).
After initial exposure, more immune-competent persons develop asymptomatic latent …

As the goal of a bacterium is to become bacteria, evolution has imposed continued
selections for gene expression. The intracellular pathogen Mycobacterium tuberculosis, the …

The emergence of multidrug resistance (MDR), extensively drug‐resistant, and total drug‐
resistant Mycobacterium tuberculosis (Mtb) strains have hampered the treatment of …