Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …

The calibrated application of limited-duration, cyclic, moderately intense hypoxia-
reoxygenation increases cardiac resistance to ischemia-reperfusion stress. These …

The ability to sense and respond to oxygen deprivation is required for survival; thus,
understanding the mechanisms by which changes in oxygen are linked to cell viability and …

Since a constant supply of oxygen is essential to sustain life, organisms have evolved
multiple defence mechanisms to ensure maintenance of the delicate balance between …

Aims: Human embryonic stem cell derived-cardiovascular progenitor cells (hESC-CVPCs)
are a promising cell source for cardiac repair, while the underlying mechanisms need to be …

The role of mitochondrial permeability transition pore (MPTP) in the mechanism of
intermittent high altitude (IHA) hypoxic adaptation is not understood. Therefore, we study …

Intermittent hypobaric hypoxia (IHH) protects hearts against ischemia-reperfusion (I/R)
injury, but the underlying mechanisms are far from clear. ROS are paradoxically regarded as …

We have previously demonstrated that intermittent high-altitude (IHA) hypoxia significantly
attenuates ischemia-reperfusion (I/R) injury-induced excessive increase in resting …

Background/Aims: Chronic intermittent hypobaric hypoxia (CIHH) protects the heart against
ischemia/reperfusion (I/R) injury. This study investigated the calcium homeostasis …

Intermittent hypobaric hypoxia (IHH) preconditioning protects the heart against ischemic
injuries. However, little is known about the therapeutic effect of IHH on myocardial infarction …