Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

Recent transcriptome analyses have revealed that noncoding RNAs (ncRNAs) are broadly
expressed in mammalian cells and abundant in the CNS, with tissue and cell type-specific …

The m 6 A reader YT521-B homology containing 2 (YTHDC2) has been identified to inhibit
lung adenocarcinoma (LUAD) tumorigenesis by suppressing solute carrier 7A11 (SLC7A11) …

Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a
trinucleotide repeat expansion in the huntingtin (HTT) gene, which is expressed ubiquitously …

Neurodegenerative diseases (NDs) are becoming increasingly prevalent in the world, with
an aging population. In the last few decades, due to the devastating nature of these …

Neurodegenerative diseases are debilitating and currently incurable conditions causing
severe cognitive and motor impairments, defined by the progressive deterioration of …

MicroRNAs are small noncoding RNAs that regulate gene expression at the
posttranscriptional level in a sequence-specific manner. After their discovery in 1993 …

The emerging complexity of the transcriptional landscape poses great challenges to our
conventional preconceptions of how the genome regulates brain function and dysfunction …

Objective: The goal of this study was to compare the microRNA (miRNA) profile of
Parkinson's disease (PD) frontal cortex with normal control brain, allowing for the …

Aging-related neurodegenerative diseases are progressive and fatal neurological diseases
that are characterized by irreversible neuron loss and gliosis. With a growing population of …