Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances

SM Hosseini, B Borys, S Karimi-Abdolrezaee - Brain, 2024 - academic.oup.com
Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …

Metal–Organic Frameworks for Nerve Repair and Neural Stem Cell Therapy

L Meng, N Ren, M Dong, S Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Recently, neurological disorders have led to a growing global burden of fatalities and
disabilities. The limited capacity for natural self‐regeneration poses a significant challenge …

Mesenchymal stem cells: from identification and characterization to clinical applications

M Alvarez-Viejo, KH Haider - Handbook of stem cell therapy, 2022 - Springer
Since Friedenstein and co-workers first reported bone marrow-derived mesenchymal stem
cells (MSCs) during the early 1970s, several researchers have focused on their biology and …

Combining cell therapy with human autologous Schwann cell and bone marrow-derived mesenchymal stem cell in patients with subacute complete spinal cord injury …

S Oraee-Yazdani, M Akhlaghpasand… - Stem Cell Research & …, 2021 - Springer
Background Cellular transplantations have promising effects on treating spinal cord injury
(SCI) patients. Mesenchymal stem cells (MSCs) and Schwann cells (SCs), which have safety …

[HTML][HTML] Multiple strategies enhance the efficacy of MSCs transplantation for spinal cord injury

QM Pang, KQ Deng, M Zhang, XC Wu, RL Yang… - Biomedicine & …, 2023 - Elsevier
Spinal cord injury (SCI) is a serious complication of the central nervous system (CNS) after
spine injury, often resulting in severe sensory, motor, and autonomic dysfunction below the …

The comparative effects of mesenchymal stem cell transplantation therapy for spinal cord injury in humans and animal models: a systematic review and meta-analysis

LDV Johnson, MR Pickard, WEB Johnson - Biology, 2021 - mdpi.com
Simple Summary The effects of mesenchymal stem cell (MSC) transplants on functional
recovery after spinal cord injury have been compared in humans and animal models. Data …

Neural stem cell transplantation inhibits glial cell proliferation and P2X receptor-mediated neuropathic pain in spinal cord injury rats

XJ Du, YX Chen, ZC Zheng, N Wang… - Neural regeneration …, 2019 - journals.lww.com
Abstract P2X4 and P2X7 receptors play an important role in neuropathic pain after spinal
cord injury. Regulation of P2X4 and P2X7 receptors can obviously reduce pain …

Safety and feasibility of autologous olfactory ensheathing cell and bone marrow mesenchymal stem cell co-transplantation in chronic human spinal cord injury: a …

H Zamani, M Soufizomorrod, S Oraee-Yazdani… - Spinal Cord, 2022 - nature.com
Study design This is a phase I clinical trial. Objectives Our objective was to assess the safety
and feasibility of autologous mucosal olfactory ensheathing cell (OEC) and bone marrow …

Stem cell treatment trials of spinal cord injuries in animals

MF Farid, YS Abouelela, H Rizk - Autonomic Neuroscience, 2022 - Elsevier
Background Spinal cord injury (SCI) is a serious neurological spinal cord damage that
resulted in the loss of temporary or permanent function. However, there are even now no …

Bibliometric analysis of global research on the rehabilitation of spinal cord injury in the past two decades

X Liu, N Liu, M Zhou, Y Lu, F Li - Therapeutics and clinical risk …, 2018 - Taylor & Francis
Purpose We aimed to build a model to qualitatively and quantitatively evaluate publications
of research of spinal cord injury rehabilitation from 1997 to 2016. Methods Data were …