Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

The biology of bone healing is a rapidly developing science. Advances in transgenic and
gene‐targeted mice have enabled tissue and cell‐specific investigations of skeletal …

Vascular endothelial growth factor-A (VEGF-A) is a key mediator of angiogenesis, signalling
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …

Chronic wounds are defined as wounds that fail to proceed through the normal phases of
wound healing in an orderly and timely manner. The most common and inevitable …

Extracellular vesicles have shown good potential in disease treatments including ischemic
injury such as myocardial infarction. However, the efficient production of highly active …

Bone has well documented natural healing capacity that normally is sufficient to repair
fractures and other common injuries. However, the properties of bone change throughout …

Significance: Angiogenesis, the growth of new blood vessels from existing vessels, is an
important aspect of the repair process. Restoration of blood flow to damaged tissues …

Inflammation is ubiquitous in the body, triggering desirable immune response to defend
against dangerous signals or instigating undesirable damage to cells and tissues to cause …

Background: This article outlines therapeutic mechanisms of hyperbaric oxygen therapy and
reviews data on its efficacy for clinical problems seen by plastic and reconstructive …

Bone vasculature plays a vital role in bone development, remodeling and homeostasis. New
blood vessel formation is crucial during both primary bone development as well as fracture …