New approaches to cryopreservation of cells, tissues, and organs

MJ Taylor, BP Weegman, SC Baicu… - Transfusion Medicine and …, 2019 - karger.com
In this concept article, we outline a variety of new approaches that have been conceived to
address some of the remaining challenges for developing improved methods of …

Desiccation-tolerance in lichens: a review

I Kranner, R Beckett, A Hochman, TH Nash III - The Bryologist, 2008 - BioOne
Desiccation-tolerance, the ability to revive from the air-dried state, is found in prokaryotes,
algae and bryophytes, and occasionally in pteridophytes, but is very rare in the vegetative …

Constraints of tolerance: why are desiccation-tolerant organisms so small or rare?

P Alpert - Journal of Experimental Biology, 2006 - journals.biologists.com
Drying to equilibrium with the air kills nearly all animals and flowering plants, including
livestock and crops. This makes drought a key ecological problem for terrestrial life and a …

The limits and frontiers of desiccation-tolerant life

P Alpert - Integrative and comparative biology, 2005 - academic.oup.com
Drying to equilibrium with the air is lethal to most species of animals and plants, making
drought (ie, low external water potential) a central problem for terrestrial life and a major …

Biopreservation of red blood cells–the struggle with hemoglobin oxidation

T Kanias, JP Acker - The FEBS journal, 2010 - Wiley Online Library
One of the least recognized causes of cellular damage during ex vivo preservation of red
blood cells is oxidative injury to the hemoglobin. The latter has been associated with …

Long-Range Influence of Carbohydrates on the Solvation Dynamics of Water Answers from Terahertz Absorption Measurements and Molecular Modeling …

M Heyden, E Bründermann, U Heugen… - Journal of the …, 2008 - ACS Publications
We present new terahertz (THz) spectroscopic measurements of solvated sugars and
compare the effect of two disaccharides (trehalose and lactose) and one monosaccharide …

Trehalose transporter 1, a facilitated and high-capacity trehalose transporter, allows exogenous trehalose uptake into cells

T Kikawada, A Saito, Y Kanamori… - Proceedings of the …, 2007 - National Acad Sciences
Trehalose is potentially a useful cryo-or anhydroprotectant molecule for cells and
biomolecules such as proteins and nucleotides. A major obstacle to application is that …

A reoptimized GROMOS force field for hexopyranose‐based carbohydrates accounting for the relative free energies of ring conformers, anomers, epimers …

HS Hansen, PH Hünenberger - Journal of computational …, 2011 - Wiley Online Library
This article presents a reoptimization of the GROMOS 53A6 force field for hexopyranose‐
based carbohydrates (nearly equivalent to 45A4 for pure carbohydrate systems) into a new …

Intracellular delivery of trehalose for cell banking

S Stewart, X He - Langmuir, 2018 - ACS Publications
Advances in stem cell technology and regenerative medicine have underscored the need for
effective banking of living cells. Cryopreservation, using very low temperatures to achieve …

Desiccation tolerance: from genomics to the field

O Leprince, J Buitink - Plant Science, 2010 - Elsevier
Desiccation tolerance is defined as the ability to survive the removal of all, or almost all the
cellular water without irreversible damage. It confers to dried organisms the ability to survive …