Sleep and epilepsy: A snapshot of knowledge and future research lines

L Nobili, B Frauscher, S Eriksson… - Journal of sleep …, 2022 - Wiley Online Library
Sleep and epilepsy have a reciprocal relationship, and have been recognized as bedfellows
since antiquity. However, research on this topic has made a big step forward only in recent …

Bidirectional relationships of sleep and epilepsy in adults with epilepsy

M Grigg-Damberger, N Foldvary-Schaefer - Epilepsy & Behavior, 2021 - Elsevier
This targeted review addresses the best accepted and most intriguing recent observations
on the complex relationships between sleep and epilepsy. Ten to 15% of all epilepsies are …

Spike patterns surrounding sleep and seizures localize the seizure‐onset zone in focal epilepsy

EC Conrad, AY Revell, AS Greenblatt, RS Gallagher… - …, 2023 - Wiley Online Library
Objective Interictal spikes help localize seizure generators as part of surgical planning for
drug‐resistant epilepsy. However, there are often multiple spike populations whose …

Rapid eye movement sleep affects interictal epileptic activity differently in mesiotemporal and neocortical areas

A Ho, S Hannan, J Thomas, T Avigdor, C Abdallah… - …, 2023 - Wiley Online Library
Objective Rapid eye movement (REM) sleep reduces the rate and extent of interictal
epileptiform discharges (IEDs). Breakthrough epileptic activity during REM sleep is therefore …

Sleep, oscillations, and epilepsy

C Bernard, B Frauscher, J Gelinas, I Timofeev - Epilepsia, 2023 - Wiley Online Library
Sleep and wake are defined through physiological and behavioral criteria and can be
typically separated into non‐rapid eye movement (NREM) sleep stages N1, N2, and N3 …

Advances in electrical source imaging: a review of the current approaches, applications and challenges

I Zorzos, I Kakkos, EM Ventouras, GK Matsopoulos - Signals, 2021 - mdpi.com
Brain source localization has been consistently implemented over the recent years to
elucidate complex brain operations, pairing the high temporal resolution of the EEG with the …

Prevalence and localization of nocturnal epileptiform discharges in mild cognitive impairment

R Ciliento, K Gjini, K Dabbs, B Hermann… - Brain …, 2023 - academic.oup.com
Recent evidence shows that identifying and treating epileptiform abnormalities in patients
with Alzheimer's disease could represent a potential avenue to improve clinical outcome …

Acoustoelectric imaging of deep dipoles in a human head phantom for guiding treatment of epilepsy

A Barragan, C Preston, A Alvarez, T Bera… - Journal of neural …, 2020 - iopscience.iop.org
Objective. This study employs a human head model with real skull to demonstrate the
feasibility of transcranial acoustoelectric brain imaging (tABI) as a new modality for electrical …

Neuromodulation by means of phase-locked auditory stimulation affects key marker of excitability and connectivity during sleep

G Sousouri, E Krugliakova, J Skorucak, S Leach… - Sleep, 2022 - academic.oup.com
The propagating pattern of sleep slow waves (high-amplitude oscillations< 4.5 Hz) serves as
a blueprint of cortical excitability and brain connectivity. Phase-locked auditory stimulation is …

Untangling a web: basic mechanisms of the complex interactions between sleep, circadian rhythms, and epilepsy

RK Maganti, MV Jones - Epilepsy Currents, 2021 - journals.sagepub.com
Seizures have sleep–wake and circadian patterns in various epilepsies and, in turn, disrupt
sleep and circadian rhythms. The resultant sleep deprivation (SD) is an exacerbating factor …