[HTML][HTML] Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion

TM Eser, O Baranov, M Huth, MIM Ahmed… - Nature …, 2023 - nature.com
Despite intensive research since the emergence of SARS-CoV-2, it has remained unclear
precisely which components of the early immune response protect against the development …

Symptom propagation in respiratory pathogens of public health concern: a review of the evidence

P Asplin, R Mancy, T Finnie… - Journal of the …, 2024 - royalsocietypublishing.org
Symptom propagation occurs when the symptom set an individual experiences is correlated
with the symptom set of the individual who infected them. Symptom propagation may …

[HTML][HTML] Enhanced Spike-specific, but attenuated Nucleocapsid-specific T cell responses upon SARS-CoV-2 breakthrough versus non-breakthrough infections

MIM Ahmed, P Diepers, C Janke, M Plank… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 vaccine breakthrough infections frequently occurred even before the
emergence of Omicron variants. Yet, relatively little is known about the impact of vaccination …

[HTML][HTML] Studying temporal titre evolution of commercial SARS-CoV-2 assays reveals significant shortcomings of using BAU standardization for comparison

I Kroidl, S Winter, R Rubio-Acero, A Bakuli… - Virology Journal, 2023 - Springer
Background Measuring specific anti-SARS-CoV-2 antibodies has become one of the main
epidemiological tools to survey the ongoing SARS-CoV-2 pandemic, but also vaccination …

[HTML][HTML] Uncovering the Contrasts and Connections in PASC: Viral Load and Cytokine Signatures in Acute COVID-19 versus Post-Acute Sequelae of SARS-CoV-2 …

B Compeer, TR Neijzen, SFL van Lelyveld… - Biomedicines, 2024 - mdpi.com
The recent global COVID-19 pandemic has had a profound and enduring impact, resulting
in substantial loss of life. The scientific community has responded unprecedentedly by …

Nasopharyngeal Viral Load Is the Major Driver of Incident Antibody Immune Response to SARS-CoV-2 Infection

M Xu, MP O'Brien, AT Hooper… - Open Forum …, 2023 - academic.oup.com
Background Virologic determinants of seroconversion to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection were defined in a post hoc analysis of prospectively …

Plasma SARS‐CoV‐2 RNA elimination and RAGE kinetics distinguish COVID‐19 severity

X Deng, P Gantner, J Forestell… - Clinical & …, 2023 - Wiley Online Library
Objectives Identifying biomarkers causing differential SARS‐CoV‐2 infection kinetics
associated with severe COVID‐19 is fundamental for effective diagnostics and therapeutic …

[HTML][HTML] SARS-CoV-2 viremia but not respiratory viral load is associated with respiratory complications in patients with severe COVID-19

L Chen, LB Olson, IA Naqvi, BA Sullenger… - BMC Pulmonary …, 2024 - Springer
Background Severe COVID-19 carries a high morbidity and mortality. Previous studies have
shown an association between COVID-19 severity and SARS-CoV-2 viral load (VL). We …

[HTML][HTML] Impact of Omicron Variant Infection on Assessment of Spike-Specific Immune Responses Using the EUROIMMUN Quan-T-Cell SARS-CoV-2 Assay and …

MIM Ahmed, M Plank, N Castelletti, P Diepers, TM Eser… - Diagnostics, 2023 - mdpi.com
The currently prevailing variants of SARS-CoV-2 are subvariants of the Omicron variant. The
aim of this study was to analyze the effect of mutations in the Spike protein of Omicron on the …

[HTML][HTML] Early nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways and reduced systemic inflammation before …

TM Eser, O Baranov, M Huth, MIM Ahmed, F Deák… - 2022 - europepmc.org
Despite intensive research since the emergence of SARS-CoV-2, it has remained unclear
precisely which components of the early immune response protect against the development …