Adenocarcinoma spectrum lesions of the lung: Detection, pathology and treatment strategies

L Succony, DM Rassl, AP Barker, FM McCaughan… - Cancer treatment …, 2021 - Elsevier
Adenocarcinoma has become the most prevalent lung cancer sub-type and its frequency is
increasing. The earliest stages in the development of lung adenocarcinomas are visible …

[HTML][HTML] Molecular heterogeneity in lung cancer: from mechanisms of origin to clinical implications

FZ Marino, R Bianco, M Accardo, A Ronchi… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
Molecular heterogeneity is a frequent event in cancer responsible of several critical issues in
diagnosis and treatment of oncologic patients. Lung tumours are characterized by high …

Comprehensive next-generation sequencing unambiguously distinguishes separate primary lung carcinomas from intrapulmonary metastases: comparison with …

JC Chang, D Alex, M Bott, KS Tan, V Seshan… - Clinical Cancer …, 2019 - AACR
Purpose: In patients with> 1 non–small cell lung carcinoma (NSCLC), the distinction
between separate primary lung carcinomas (SPLCs) and intrapulmonary metastases (IPMs) …

[HTML][HTML] EGFR TKIs plus WBRT demonstrated no survival benefit other than that of TKIs alone in patients with NSCLC and EGFR mutation and brain metastases

T Jiang, C Su, X Li, C Zhao, F Zhou, S Ren… - Journal of Thoracic …, 2016 - Elsevier
Introduction Whether EGFR tyrosine kinase inhibitors (TKIs) plus whole brain radiation
therapy (WBRT) provide a better survival benefit than EGFR TKIs alone remains …

Multiple primary lung cancer: Updates of clinical management and genomic features

H Tian, G Bai, Z Yang, P Chen, J Xu, T Liu, T Fan… - Frontiers in …, 2023 - frontiersin.org
In recent decades, multiple primary lung cancer (MPLC) has been increasingly prevalent in
clinical practice. However, many details about MPLC have not been completely settled, such …

[HTML][HTML] Pulmonary ground-glass opacity: computed tomography features, histopathology and molecular pathology

JW Gao, S Rizzo, LH Ma, XY Qiu, A Warth… - … lung cancer research, 2017 - ncbi.nlm.nih.gov
The incidence of pulmonary ground-glass opacity (GGO) lesions is increasing as a result of
the widespread use of multislice spiral computed tomography (CT) and the low-dose CT …

[HTML][HTML] Ground-glass nodules of the lung in never-smokers and smokers: clinical and genetic insights

Y Kobayashi, C Ambrogio… - Translational lung cancer …, 2018 - ncbi.nlm.nih.gov
Pulmonary ground-glass nodules (GGNs) are hazy radiological findings on computed
tomography (CT). GGNs are detected more often in never-smokers. Retrospective and …

Pulmonary invasive mucinous adenocarcinoma

WC Chang, YZ Zhang, AG Nicholson - Histopathology, 2024 - Wiley Online Library
Invasive mucinous adenocarcinoma (IMA) is a relatively rare subtype of lung
adenocarcinoma, composed of goblet and/or columnar tumour cells containing abundant …

Clinical efficacy of first-generation EGFR-TKIs in patients with advanced non-small-cell lung cancer harboring EGFR exon 20 mutations

D Chen, Z Song, G Cheng - OncoTargets and therapy, 2016 - Taylor & Francis
Purpose Subsets of non-small-cell lung cancer patients with epidermal growth factor
receptor (EGFR) mutations carry uncommon subtypes. We evaluated the efficacy of first …

Discrepancy of epidermal growth factor receptor mutation in lung adenocarcinoma presenting as multiple ground-glass opacities

M Liu, WX He, N Song, Y Yang… - European Journal of …, 2016 - academic.oup.com
OBJECTIVES To identify epidermal growth factor receptor (EGFR) mutation status between
different lesions in lung adenocarcinoma presenting as multiple ground-glass opacity (GGO) …