Ki-67: level of evidence and methodological considerations for its role in the clinical management of breast cancer: analytical and critical review

E Luporsi, F André, F Spyratos, PM Martin… - Breast cancer research …, 2012 - Springer
Clinicians can use biomarkers to guide therapeutic decisions in estrogen receptor positive
(ER+) breast cancer. One such biomarker is cellular proliferation as evaluated by Ki-67. This …

[HTML][HTML] Biomarkers in triple negative breast cancer: A review

BS Yadav, P Chanana, S Jhamb - World journal of clinical oncology, 2015 - ncbi.nlm.nih.gov
Breast cancer is an intrinsically heterogeneous disease. In the world about 1 million cases of
breast cancer are diagnosed annually and more than 170000 are triple-negative …

Ki67 measured after neoadjuvant chemotherapy for primary breast cancer

G Von Minckwitz, WD Schmitt, S Loibl, BM Müller… - Clinical cancer …, 2013 - AACR
Abstract Purpose: The value of Ki67 measured on residual disease after neoadjuvant
chemotherapy is not sufficiently described. Experimental Design: Participants of the …

[HTML][HTML] Residual proliferative cancer burden to predict long-term outcome following neoadjuvant chemotherapy

A Sheri, IE Smith, SR Johnston, R A'hern, A Nerurkar… - Annals of …, 2015 - Elsevier
Background The purpose of this study was (i) to test the hypothesis that combining Ki67 with
residual cancer burden (RCB) following neoadjuvant chemotherapy, as the residual …

Breast cancer Ki67 expression prediction by DCE-MRI radiomics features

W Ma, Y Ji, L Qi, X Guo, X Jian, P Liu - Clinical radiology, 2018 - Elsevier
Aim To investigate whether quantitative radiomics features extracted from dynamic contrast-
enhanced magnetic resonance imaging (DCE-MRI) are associated with Ki67 expression of …

[HTML][HTML] Prognostic importance of Ki-67 in breast cancer and its relationship with other prognostic factors

G Kanyılmaz, BB Yavuz, M Aktan… - European journal of …, 2019 - ncbi.nlm.nih.gov
Objective The clinical feature of breast cancer is very heterogeneous because of the
variable prognostic factors impact its behaviour. The aim of study is to find the prognostic …

Clinicopathological significance of androgen receptor, HER2, Ki-67 and EGFR expressions in salivary duct carcinoma

T Masubuchi, Y Tada, S Maruya, Y Osamura… - International journal of …, 2015 - Springer
Background Salivary duct carcinoma (SDC) is a highly aggressive disease which often
metastasizes to distant sites, and there is no established standard therapy for this systemic …

Changes in the ER, PgR, HER2, p53 and Ki-67 biological markers between primary and recurrent breast cancer: discordance rates and prognosis

R Nishimura, T Osako, Y Okumura, R Tashima… - World journal of surgical …, 2011 - Springer
Background In breast cancer, ER/PgR, HER2, and Ki-67 are important biological markers for
predicting prognosis and making effective treatment decisions. In addition, changes in …

[HTML][HTML] Quantitative assessment Ki-67 score for prediction of response to neoadjuvant chemotherapy in breast cancer

JR Brown, MP DiGiovanna, B Killelea, DR Lannin… - Laboratory …, 2014 - Elsevier
Measurement of Ki-67, a marker of cell proliferation, has been associated with response to
therapy, but methods of measurement are controversial. Here we use a quantitative …

[HTML][HTML] Neoadjuvant approach as a platform for treatment personalization: focus on HER2-positive and triple-negative breast cancer

F Miglietta, MV Dieci, G Griguolo, V Guarneri - Cancer Treatment Reviews, 2021 - Elsevier
The neoadjuvant setting provides unquestionable clinical benefits for high-risk breast cancer
(BC) patients, mainly in terms of expansion of locoregional treatment options and prognostic …