Combinatorial approaches in post-polymerization modification for rational development of therapeutic delivery systems

Y Zhong, BJ Zeberl, X Wang, J Luo - Acta biomaterialia, 2018 - Elsevier
The combinatorial polymer library approach has been proven to be effective for the
optimization of therapeutic delivery systems. The library of polymers with chemical diversity …

Introducing the azlactone functionality into polymers through controlled radical polymerization: strategies and recent developments

HT Ho, ME Levere, D Fournier… - Australian Journal of …, 2012 - CSIRO Publishing
Polymers containing the highly reactive azlactone group have emerged as a powerful
platform useful in various application areas. This Highlight summarizes recent developments …

Nanoparticle (Star Polymer) Delivery of Nitric Oxide Effectively Negates Pseudomonas aeruginosa Biofilm Formation

HTT Duong, K Jung, SK Kutty, S Agustina… - …, 2014 - ACS Publications
Biofilms are increasingly recognized as playing a major role in human infectious diseases,
as they can form on both living tissues and abiotic surfaces, with serious implications for …

The use of nanoparticles to deliver nitric oxide to hepatic stellate cells for treating liver fibrosis and portal hypertension

HTT Duong, Z Dong, L Su, C Boyer, J George… - Small, 2015 - Wiley Online Library
Polymeric nanoparticles are designed to transport and deliver nitric oxide (NO) into hepatic
stellate cells (HSCs) for the potential treatment of both liver fibrosis and portal hypertension …

Design of thermoresponsive polymers with aqueous LCST, UCST, or both: modification of a reactive poly (2-vinyl-4, 4-dimethylazlactone) scaffold

Y Zhu, R Batchelor, AB Lowe, PJ Roth - Macromolecules, 2016 - ACS Publications
The synthesis and aqueous solution properties of a family of zwitterionic homo-, co-, and
terpolymers derived from poly (2-vinyl-4, 4-dimethylazlactone)(pVDMA) with tunable lower …

Romp-based glycopolymers with high affinity for mannose-binding lectins

C Gonnot, M Scalabrini, B Roubinet, C Ziane… - …, 2023 - ACS Publications
Well-defined, highly reactive poly (norbornenyl azlactone) s of controlled length (number-
average degree of polymerization DP n¯= 10 to 1,000) were made by ring-opening …

Doubly thermo-responsive ABC triblock copolymer nanoparticles prepared through dispersion RAFT polymerization

Q Li, C Gao, S Li, F Huo, W Zhang - Polymer Chemistry, 2014 - pubs.rsc.org
Doubly thermo-responsive triblock copolymer nanoparticles of poly (N-isopropylacrylamide)-
block-poly [N, N-(dimethylamino) ethyl methacrylate]-block-polystyrene (PNIPAM-b …

Soft Matter Nanoparticles with Reactive Coronal Pentafluorophenyl Methacrylate Residues via Non‐Polar RAFT Dispersion Polymerization and Polymerization …

Y Pei, JM Noy, PJ Roth, AB Lowe - Journal of Polymer Science …, 2015 - Wiley Online Library
Soft matter nanoparticles exhibiting rich polymorphism with reactive pentafluorophenyl
methacrylate (PFPMA) units in their coronae were prepared via non‐polar reversible …

[HTML][HTML] NIR laser-responsive PNIPAM and gold nanorod composites for the engineering of thermally reactive drug delivery nanomedicine

Y Kwon, Y Choi, J Jang, S Yoon, J Choi - Pharmaceutics, 2020 - mdpi.com
When ingesting a drug on its own or injecting it directly into tissue, its concentration
increases immediately within the body, which often exacerbates the side effects and …

Trithiocarbonates in RAFT polymerization

G Moad - RAFT Polymerization: Methods, Synthesis and …, 2021 - Wiley Online Library
This chapter provides a review of the synthesis, reactions, and applications of
trithiocarbonates, R′ SC ( S) SR, in radical polymerization with reversible addition …