Throughout development, the brain transits from early highly synchronous activity patterns to
a mature state with sparse and decorrelated neural activity, yet the mechanisms underlying …

Spontaneous activity generated before the onset of sensory transduction has a key role in
wiring developing sensory circuits. From axonal targeting, to synapse formation and …

The sensory cortex underlies our ability to perceive and interact with the external world.
Sensory perceptions are controlled by specialized neuronal circuits established through fine …

The experience of coupling between motor output and visual feedback is necessary for the
development of visuomotor skills and shapes visuomotor integration in visual cortex …

The developing visual thalamus and cortex extract positional information encoded in the
correlated activity of retinal ganglion cells by synaptic plasticity, allowing for the refinement …

In utero brain development underpins brain health across the lifespan but is vulnerable to
physiological and pharmacological perturbation. Here, we show that antiepileptic …

Hematopoietic stem cells (HSCs) are produced from the blood vessel walls and circulate in
the blood during the perinatal period. However, the migration dynamics of how HSCs enter …

The accumulation of alpha-synuclein (α-Syn) into Lewy bodies in cortical and subcortical
regions has been linked to the pathogenesis of synucleinopathies such as Parkinson's …

The development and function of sensory systems require intact glutamatergic
neurotransmission. Changes in touch sensation and vision are common symptoms in autism …

The cerebral cortex comprises a complex and exquisite network of neuronal circuits that is
formed during development. To explore the molecular mechanisms involved in cortical …