Treatment of Carbapenem-Resistant Enterobacteriaceae Infections in Children

K Chiotos, M Hayes, JS Gerber… - Journal of the Pediatric …, 2020 - academic.oup.com
Infections due to carbapenem-resistant Enterobacteriaceae (CRE) are increasingly
prevalent in children and are associated with poor clinical outcomes. Optimal treatment …

Multidrug-resistant organisms in urinary tract infections in children

M Mahony, B McMullan, J Brown, SE Kennedy - Pediatric Nephrology, 2020 - Springer
The global spread of multidrug-resistant organisms has led to an increase in urinary tract
infections (UTIs) in children that are difficult to treat. This review explores the current …

Carbapenem-resistant gram-negative bacterial infections in children

D Aguilera-Alonso, L Escosa-García… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Carbapenem-resistant organisms (CRO) are a major global public health threat.
Enterobacterales hydrolyze almost all β-lactams through carbapenemase production …

Clinical and bacterial risk factors for mortality in children with carbapenem-resistant Enterobacteriaceae bloodstream infections in India

LEB Nabarro, C Shankar, AK Pragasam… - The Pediatric …, 2017 - journals.lww.com
Background: Carbapenem-resistant Enterobacteriaceae (CRE) are an increasing cause of
nosocomial infection in hospitalized children worldwide. Few studies have investigated risk …

[HTML][HTML] Dose optimisation based on pharmacokinetic/pharmacodynamic target of tigecycline

B Leng, G Yan, C Wang, C Shen, W Zhang… - Journal of Global …, 2021 - Elsevier
Tigecycline, a new first-in-class glycylcycline antibiotic, has shown promising efficacy
against a broad range of micro-organisms. It is widely prescribed for various infections, with …

Clonal spread of carbapenem-resistant Klebsiella pneumoniae among patients at admission and discharge at a Vietnamese neonatal intensive care unit

B Berglund, NTB Hoang, L Lundberg, NK Le… - … Resistance & Infection …, 2021 - Springer
Background The increasing prevalence of carbapenem-resistant Enterobacteriaceae (CRE)
is a growing problem globally, particularly in low-to middle-income countries (LMICs) …

Use of newer and repurposed antibiotics against gram-negative bacteria in neonates

A Kontou, M Kourti, E Iosifidis, K Sarafidis, E Roilides - Antibiotics, 2023 - mdpi.com
Antimicrobial resistance has become a significant public health problem globally with
multidrug resistant Gram negative (MDR-GN) bacteria being the main representatives. The …

Mycobacterium abscessus Complex Infections in Children: A Review

AP Sabin, P Ferrieri, S Kline - Current infectious disease reports, 2017 - Springer
Abstract Purpose of Review Infections in children with Mycobacterium abscessus complex
represent a particular challenge for clinicians. Increasing incidence of these infections …

Optimal management of complicated infections in the pediatric patient: the role and utility of ceftazidime/avibactam

M Bassetti, M Peghin, A Mesini… - Infection and Drug …, 2020 - Taylor & Francis
Antimicrobial resistance poses a substantial threat to global public health. The pursuit of
new antibiotics has decreased and very few options have been investigated for the …

Use of tigecycline in pediatric clinical practice

MV Mastrolia, L Galli, M De Martino… - Expert Review of Anti …, 2017 - Taylor & Francis
Introduction: Tigecycline, a derivative of minocycline, is an extended-spectrum antimicrobial
agent. It has a restricted approval field in children and the experience of its adoption in …