Background: Seed-based studies on resting-state functional connectivity (rsFC) in
schizophrenia have shown disrupted connectivity involving a number of brain networks; …

Abstract Since Emil Kraepelin's conceptualization of endogenous psychoses as dementia
praecox and manic depression, the separation between primary psychotic disorders and …

Schizophrenia is a complex mental disorder with disorganized communication among large-
scale brain networks, as demonstrated by impaired resting-state functional connectivity …

Recent theoretical accounts have proposed excitation and inhibition (E/I) imbalance as a
possible mechanistic, network-level hypothesis underlying neural and behavioral …

Glutamatergic and GABAergic dysfunction are implicated in the pathophysiology of
schizophrenia. Previous work has shown relationships between glutamate, GABA, and brain …

To better characterize hippocampal pathophysiology in schizophrenia, we conducted a
longitudinal study evaluating hippocampal functional connectivity during resting state, using …

A number of neuroimaging studies have provided evidence in support of the hypothesis that
faulty interactions between spatially disparate brain regions underlie the pathophysiology of …

A growing body of evidence suggests glutamate excess in schizophrenia and that N-methyl-
d-aspartate receptor (NMDAR) hypofunction on γ-aminobutyric acid (GABA) interneurons …

Objective To describe abnormalities in large scale functional networks in unmedicated
patients with schizophrenia and to examine effects of risperidone on networks. Material and …

Evidence points toward a relationship between longer duration of untreated psychosis
(DUP) and worse long-term outcomes in patients with first episode psychosis (FEP), but the …