Biological roles of adenine methylation in RNA
K Boulias, EL Greer - Nature Reviews Genetics, 2023 - nature.com
Abstract N 6-Methyladenosine (m6A) is one of the most abundant modifications of the
epitranscriptome and is found in cellular RNAs across all kingdoms of life. Advances in …
epitranscriptome and is found in cellular RNAs across all kingdoms of life. Advances in …
The role of m6A modification in the biological functions and diseases
X Jiang, B Liu, Z Nie, L Duan, Q Xiong, Z Jin… - Signal transduction and …, 2021 - nature.com
Abstract N6-methyladenosine (m6A) is the most prevalent, abundant and conserved internal
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
Where, when, and how: context-dependent functions of RNA methylation writers, readers, and erasers
Cellular RNAs are naturally decorated with a variety of chemical modifications. The
structural diversity of the modified nucleosides provides regulatory potential to sort groups of …
structural diversity of the modified nucleosides provides regulatory potential to sort groups of …
The molecular biology of FMRP: new insights into fragile X syndrome
JD Richter, X Zhao - Nature Reviews Neuroscience, 2021 - nature.com
Fragile X mental retardation protein (FMRP) is the product of the fragile X mental retardation
1 gene (FMR1), a gene that—when epigenetically inactivated by a triplet nucleotide repeat …
1 gene (FMR1), a gene that—when epigenetically inactivated by a triplet nucleotide repeat …
The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders
Stress is a primary risk factor for several neuropsychiatric disorders. Evidence from
preclinical models and clinical studies of depression have revealed an array of structural …
preclinical models and clinical studies of depression have revealed an array of structural …
m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome
Abstract N 6-Methyladenosine (m6A) is the most prevalent RNA modification on mRNAs and
lncRNAs. It plays a pivotal role during various biological processes and disease …
lncRNAs. It plays a pivotal role during various biological processes and disease …
METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer's disease through aberrant cell cycle events
Abstract Background N6-methyladenosine (m 6 A) modification of RNA influences
fundamental aspects of RNA metabolism and m 6 A dysregulation is implicated in various …
fundamental aspects of RNA metabolism and m 6 A dysregulation is implicated in various …
DirectRMDB: a database of post-transcriptional RNA modifications unveiled from direct RNA sequencing technology
With advanced technologies to map RNA modifications, our understanding of them has
been revolutionized, and they are seen to be far more widespread and important than …
been revolutionized, and they are seen to be far more widespread and important than …
Novel insights into the interplay between m6A modification and noncoding RNAs in cancer
YC Yi, XY Chen, J Zhang, JS Zhu - Molecular cancer, 2020 - Springer
Abstract N6-methyladenosine (m 6 A) is one of the most common RNA modifications in
eukaryotes, mainly in messenger RNA (mRNA). Increasing evidence shows that m 6 A …
eukaryotes, mainly in messenger RNA (mRNA). Increasing evidence shows that m 6 A …
The biogenesis and precise control of RNA m6A methylation
N 6-Methyladenosine (m 6 A) is the most prevalent internal RNA modification in mRNA, and
has been found to be highly conserved and hard-coded in mammals and other eukaryotic …
has been found to be highly conserved and hard-coded in mammals and other eukaryotic …