Synthesis and reactivity of propargylamines in organic chemistry

K Lauder, A Toscani, N Scalacci… - Chemical reviews, 2017 - ACS Publications
Propargylamines are a versatile class of compounds which find broad application in many
fields of chemistry. This review aims to describe the different strategies developed so far for …

Carbodiimide-based synthesis of N-heterocycles: moving from two classical reactive sites to chemical bond breaking/forming reaction

Y Wang, WX Zhang, Z Xi - Chemical Society Reviews, 2020 - pubs.rsc.org
Carbodiimides are a unique class of heterocumulene compounds that display distinctive
chemical properties. The rich chemistry of carbodiimides has drawn increasing attention …

New protocols to access imidazoles and their ring fused analogues: synthesis from N-propargylamines

E Vessally, S Soleimani-Amiri, A Hosseinian, L Edjlali… - Rsc Advances, 2017 - pubs.rsc.org
Imidazole and its derivatives are privileged N-heterocyclic structures present in various
natural products and synthetic pharmaceuticals. Despite the numerous methods that have …

A Highly Efficient and Eco-Friendly Synthesis of Disubstituted Imidazoles in Ionic Liquid from Gem-Dibromo Vinylarenes and Amidines

PK Gupta, MA Azzam, M Saquib… - Polycyclic Aromatic …, 2023 - Taylor & Francis
A rapid and versatile, transition metal free, green methodology for the synthesis of 2, 5-
disubstituted-1 H-imidazoles, using gem-dibromo vinylarenes and amidines is described …

Imidazoles from nitroallylic acetates and α-bromonitroalkenes with amidines: Synthesis and trypanocidal activity studies

E Gopi, T Kumar, RFS Menna-Barreto… - Organic & …, 2015 - pubs.rsc.org
Cascade reactions of amidines with nitroallylic acetates and α-bromonitroalkenes provide
potentially bioactive imidazoles in good to excellent yields in most cases. While 2, 4 …

Synthesis of imidazoles via cascade reaction of nitroallylic acetates with amidines and studies on their trypanocidal activity

T Kumar, D Verma, RFS Menna-Barreto… - Organic & …, 2015 - pubs.rsc.org
A one-pot, two step synthesis of highly substituted imidazoles has been carried out in good
to excellent yields for the first time via a cascade intermolecular aza-SN2′-intramolecular …

Synthesis of quinoline derivatives via Cu-catalyzed cascade annulation of heterocumulenes, alkynes, and diaryliodonium salts

Y Chi, H Yan, WX Zhang, Z Xi - Organic letters, 2017 - ACS Publications
CuOTf-catalyzed substituent-controlled cascade [2+ 2+ 2] and [4+ 2] annulation reactions
among heterocumulenes, alkynes, and diaryliodonium salts were achieved. Various …

Preparation of 1,2,5‐Trisubstituted 1H‐Imidazoles from Ketenimines and Propargylic Amines by Silver‐Catalyzed or Iodine‐Promoted Electrophilic Cyclization …

X Zhou, Z Jiang, L Xue, P Lu… - European Journal of …, 2015 - Wiley Online Library
From readily available propargylic amines, 1, 2, 5‐trisubstituted imidazoles are efficiently
obtained through a cascade reaction catalyzed by AgOTf or promoted by molecular iodine …

Synthesis of imidazole derivatives by cascade reaction: base-mediated addition/alkyne hydroamination of propargylamines and carbodiimides

JH Jia, C Yu, M Xu, JW Ma, HW Jin - Synthesis, 2015 - thieme-connect.com
A novel synthesis of 2-iminoimidazoles and 2-aminoimidazoles, via nucleophilic addition
and a subsequent sodium hydroxide mediated intramolecular alkyne hydroamination from …

[PDF][PDF] An eco-friendly approach for the synthesis of 1, 2, 5-trisubstituted and 4-amino-1, 2, 5-tetrasubstituted imidazoles via a multi-component condensation

H Mehrabi, F Alizadeh-Bami, A Meydani… - Arkivoc, 2021 - pdfs.semanticscholar.org
Abstract The synthesis of 1, 2, 5-trisubstituted and 4-amino-1, 2, 5-tetrasubstituted
imidazoles was demonstrated via a two-step cyclo-condensation reaction of aryl amines …