Cancer stem cells (CSCs) are self‐renewable cell types that are identified in most types of
liquid and solid cancers and contributed to tumor onset, expansion, resistance, recurrence …

Brain, the major organ of the central nervous system controls and processes most of body
activities. Therefore, the most aggressive brain tumor–glioblastoma and metastases from …

Cancer stem cells are critical for cancer initiation, development, and treatment resistance.
Our understanding of these processes, and how they relate to glioblastoma heterogeneity, is …

Many cancers feature cellular hierarchies that are driven by tumor-initiating cancer stem
cells (CSC) and rely on complex interactions with the tumor microenvironment. Standard cell …

Despite a deeper molecular understanding, human glioblastoma remains one of the most
treatment refractory and fatal cancers. It is known that the presence of macrophages and …

Tumor microenvironments are the result of cellular alterations in cancer that support
unrestricted growth and proliferation and result in further modifications in cell behavior …

Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …

Abstract Background Long non-coding RNAs (lncRNAs) comprise a diverse class of
transcripts that can regulate molecular and cellular processes in brain development and …

Glioblastoma is a highly angiogenetic malignancy, the neoformed vessels of which are
thought to arise by sprouting of pre-existing brain capillaries. The recent demonstration that …

Malignant gliomas, the most common type of primary brain tumor in adults, are associated
with disproportionate cancer-related morbidity and mortality. Recently, there have been …