Melanoma, a skin cancer associated with high mortality rates, is highly radio-and
chemotherapy resistant but can also be very immunogenic. These circumstances have led to …

An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as a
surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …

Background Checkpoint inhibitors are standard adjuvant treatment for stage IIB–IV resected
melanoma, but many patients recur. Our study aimed to evaluate whether mRNA-4157 …

Approximately one-half of advanced (unresectable or metastatic) melanomas harbor a
mutation in the BRAF gene, with V600E being the most common mutation. Targeted therapy …

Cancer is a major global health burden and poor survival rates can be attributed to lack of
early diagnosis and limited access to timely and standard treatments. Significant progress …

Simple Summary Cutaneous melanoma represents the most aggressive form of skin cancer
and its occurrence, development, and progression are based on the accumulation of several …

The use of biomarkers in medicine has become essential in clinical practice in order to help
with diagnosis, prognostication and prediction of treatment response. Since Alexander …

Abstract Analysis of liquid biopsies and the identification of non-invasive biomarkers for the
diagnosis and prognosis of solid tumors has grown exponentially over the last few years …

Liquid biopsies from cancer patients have the potential to improve diagnosis and prognosis.
The assessment of surrogate markers of tumor progression in circulating extracellular …

Cancer has become one of the major diseases threatening human health and life.
Circulating tumor DNA (ctDNA) testing, as a practical liquid biopsy technique, is a promising …