Synthetic approaches to 3-(2-nitroalkyl) indoles and their use to access tryptamines and related bioactive compounds

S Lancianesi, A Palmieri, M Petrini - Chemical Reviews, 2014 - ACS Publications
The assembly of architecturally complex alkaloids embedding the indole nucleus is of
paramount importance for the target oriented synthesis of biologically active molecules. 1 A …

An overview on synthetic entries to tetrahydro-β-carbolines

P Maity, D Adhikari, AK Jana - Tetrahedron, 2019 - Elsevier
The tetrahydro-β-carboline (THBC) nucleus is a predominant feature of a vast array of
naturally occurring alkaloids. Most of these alkaloids have been found to exhibit significant …

Engineering an enantioselective amine oxidase for the synthesis of pharmaceutical building blocks and alkaloid natural products

D Ghislieri, AP Green, M Pontini… - Journal of the …, 2013 - ACS Publications
The development of cost-effective and sustainable catalytic methods for the production of
enantiomerically pure chiral amines is a key challenge facing the pharmaceutical and fine …

Highly enantioselective Pictet–Spengler reaction catalyzed by SPINOL‐phosphoric acids

D Huang, F Xu, X Lin, Y Wang - Chemistry–A European Journal, 2012 - infona.pl
Chiral SPINOL‐phosphoric acids are highly enantioselective catalysts for the asymmetric
Pictet–Spengler reaction of N b‐α‐naphthylmethyl tryptamines with a series of aliphatic and …

Catalytic enantioselective nitrone cycloadditions enabling collective syntheses of indole alkaloids

X Tian, T Xuan, J Gao, X Zhang, T Liu, F Luo… - Nature …, 2024 - nature.com
Tetrahydro-β-carboline skeletons are prominent and ubiquitous in an extraordinary range of
indole alkaloid natural products and pharmaceutical compounds. Powerful synthetic …

Azomethine ylide annulations: facile access to polycyclic ring systems

C Zhang, D Das, D Seidel - Chemical Science, 2011 - pubs.rsc.org
Azomethine ylide annulations: facile access to polycyclic ring systems - Chemical Science (RSC
Publishing) DOI:10.1039/C0SC00432D Royal Society of Chemistry View PDF VersionPrevious …

Synthesis of Heterocycles through a Ruthenium‐Catalyzed Tandem Ring‐Closing Metathesis/Isomerization/N‐Acyliminium Cyclization Sequence

E Ascic, JF Jensen, TE Nielsen - Angewandte Chemie, 2011 - infona.pl
Erfolgreiches Tandem: In der Titelreaktion isomerisieren Doppelbindungen, die bei der
Ringschlussmetathese erzeugt werden, wobei reaktive Iminiumintermediate entstehen, die …

Asymmetric Synthesis of (R)‐1‐Alkyl‐Substituted Tetrahydro‐ß‐carbolines Catalyzed by Strictosidine Synthases

D Pressnitz, EM Fischereder, J Pletz… - Angewandte …, 2018 - Wiley Online Library
Stereoselective methods for the synthesis of tetrahydro‐ß‐carbolines are of significant
interest due to the broad spectrum of biological activity of the target molecules. In the plant …

Catalytic Asymmetric Alkynylation of 3, 4‐Dihydro‐β‐carbolinium Ions Enables Collective Total Syntheses of Indole Alkaloids

L Liang, S Zhou, W Zhang… - Angewandte Chemie …, 2021 - Wiley Online Library
Chiral tetrahydro‐β‐carboline (THβC) is not only a prevailing structural feature of many
natural alkaloids but also a versatile synthetic precursor for a vast array of monoterpenoid …

Conformational Adaptation of β‐Peptide Foldamers for the Formation of Metal–Peptide Frameworks

S Jeong, L Zhang, J Kim, J Gong, J Choi… - Angewandte …, 2022 - Wiley Online Library
Metal‐coordinated frameworks derived from small peptidic ligands have received much
attention thanks to peptides' vast structural and functional diversity. Various peptides with …