Nuclear physics in particle therapy: a review

M Durante, H Paganetti - Reports on Progress in Physics, 2016 - iopscience.iop.org
Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

Prompt-gamma monitoring in hadrontherapy: A review

J Krimmer, D Dauvergne, JM Létang, É Testa - Nuclear Instruments and …, 2018 - Elsevier
Secondary radiation emission induced by nuclear reactions is correlated to the path of ions
in matter. Therefore, such penetrating radiation can be used for in vivo control of …

The FLUKA code: developments and challenges for high energy and medical applications

TT Böhlen, F Cerutti, MPW Chin, A Fassò, A Ferrari… - Nuclear data sheets, 2014 - Elsevier
Abstract The FLUKA Monte Carlo code is used extensively at CERN for all beam-machine
interactions, radioprotection calculations and facility design of forthcoming projects. Such …

In vivo proton range verification: a review

AC Knopf, A Lomax - Physics in Medicine & Biology, 2013 - iopscience.iop.org
Protons are an interesting modality for radiotherapy because of their well defined range and
favourable depth dose characteristics. On the other hand, these same characteristics lead to …

The FLUKA code: an accurate simulation tool for particle therapy

G Battistoni, J Bauer, TT Boehlen, F Cerutti… - Frontiers in …, 2016 - frontiersin.org
Monte Carlo (MC) codes are increasingly spreading in the hadrontherapy community due to
their detailed description of radiation transport and interaction with matter. The suitability of a …

In vivo range verification in particle therapy

K Parodi, JC Polf - Medical physics, 2018 - Wiley Online Library
Exploitation of the full potential offered by ion beams in clinical practice is still hampered by
several sources of treatment uncertainties, particularly related to the limitations of our ability …

Range verification methods in particle therapy: underlying physics and Monte Carlo modeling

AC Kraan - Frontiers in oncology, 2015 - frontiersin.org
Hadron therapy allows for highly conformal dose distributions and better sparing of organs-
at-risk, thanks to the characteristic dose deposition as function of depth. However, the quality …

Monte Carlo simulations to support start-up and treatment planning of scanned proton and carbon ion therapy at a synchrotron-based facility

K Parodi, A Mairani, S Brons, BG Hasch… - Physics in Medicine …, 2012 - iopscience.iop.org
Reliable treatment planning of highly conformal scanned ion beam therapy demands
accurate tools for the determination and characterization of the individual pencil-like beams …

The development and clinical use of a beam ON-LINE PET system mounted on a rotating gantry port in proton therapy

T Nishio, A Miyatake, T Ogino, K Nakagawa… - International Journal of …, 2010 - Elsevier
PURPOSE: To verify the usefulness of our developed beam ON-LINE positron emission
tomography (PET) system mounted on a rotating gantry port (BOLPs-RGp) for dose–volume …

Physics controversies in proton therapy

M Engelsman, M Schwarz, L Dong - Seminars in radiation oncology, 2013 - Elsevier
The physical characteristics of proton beams are appealing for cancer therapy. The rapid
increase in operational and planned proton therapy facilities may suggest that this …