Updated recommendations regarding the management of older patients with breast cancer: a joint paper from the European Society of Breast Cancer Specialists …

L Biganzoli, NML Battisti, H Wildiers… - The Lancet …, 2021 - thelancet.com
Breast cancer is increasingly prevalent in older adults and is a substantial part of routine
oncology practice. However, management of breast cancer in this population is challenging …

Defining undertreatment and overtreatment in older adults with cancer: a scoping literature review

C DuMontier, KP Loh, PA Bain, RA Silliman… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE The terms undertreatment and overtreatment are often used to describe
inappropriate management of older adults with cancer. We conducted a comprehensive …

Practical assessment and management of vulnerabilities in older patients receiving chemotherapy: ASCO guideline for geriatric oncology

SG Mohile, W Dale, MR Somerfield… - Journal of clinical …, 2018 - ascopubs.org
Purpose To provide guidance regarding the practical assessment and management of
vulnerabilities in older patients undergoing chemotherapy. Methods An Expert Panel was …

Frailty index and all-cause and cause-specific mortality in Chinese adults: a prospective cohort study

J Fan, C Yu, Y Guo, Z Bian, Z Sun, L Yang… - The Lancet Public …, 2020 - thelancet.com
Background The fraily index is a useful proxy measure of accelerated biological ageing and
in estimating all-cause and cause-specific mortality in older individuals in European and US …

Gait speed, grip strength, and clinical outcomes in older patients with hematologic malignancies

MA Liu, C DuMontier, A Murillo… - Blood, The Journal …, 2019 - ashpublications.org
This study aimed to evaluate whether gait speed and grip strength predicted clinical
outcomes among older adults with blood cancers. We prospectively recruited 448 patients …

Practical assessment and management of vulnerabilities in older patients receiving systemic cancer therapy: ASCO guideline questions and answers

GR Williams, JO Hopkins, HD Klepin… - JCO Oncology …, 2023 - ascopubs.org
In 2023, ASCO updated its guideline on assessment and management of vulnerabilities in
older patients undergoing chemotherapy. The update revisited recommendations from the …

Frailty and the management of hematologic malignancies

GA Abel, HD Klepin - Blood, The Journal of the American …, 2018 - ashpublications.org
The majority of blood cancers occur in the elderly. This fact conspires with an aging
population in many countries to make rigorous assessment for frailty increasingly important …

Older adults with cancer and their caregivers—current landscape and future directions for clinical care

S Kadambi, KP Loh, R Dunne, A Magnuson… - Nature Reviews …, 2020 - nature.com
Despite substantial improvements in the outcomes of patients with cancer over the past two
decades, older adults (aged≥ 65 years) with cancer are a rapidly increasing population and …

Efficacy and adverse events of immunotherapy with checkpoint inhibitors in older patients with cancer

Y van Holstein, E Kapiteijn, E Bastiaannet… - Drugs & Aging, 2019 - Springer
The number of older patients with cancer is increasing as a result of the ageing of Western
societies. Immune checkpoint inhibitors have improved cancer treatment and are associated …

Patient‐reported geriatric assessment‐based frailty index among older adults with gastrointestinal malignancies

S Giri, M Al‐Obaidi, C Harmon, D Clark… - Journal of the …, 2023 - Wiley Online Library
Background Older adults with cancer are at increased risk of treatment‐related toxicities and
excess mortality. We evaluated whether a patient‐reported geriatric assessment (GA) based …