Alzheimer's disease (AD) is a progressive neurodegenerative disease with a complex and
heterogeneous pathophysiology. The number of people living with AD is predicted to …

To develop effective disease-modifying therapies for neurodegenerative diseases, reliable
markers of diagnosis, disease activity and progression are a research priority. The fact that …

Neurodegenerative diseases (ND) remains to be one of the biggest burdens on healthcare
systems and serves as a leading cause of disability and death. Alzheimer's disease (AD) is …

Cerebrospinal fluid analyses and neuroimaging can identify the underlying pathophysiology
at the earliest stage of some neurodegenerative disorders, but do not have the scalability …

Cytoplasmic TDP-43 aggregation is a pathological hallmark of amyotrophic lateral sclerosis
and frontotemporal lobar degeneration. Here we investigated the role of exosomes in the …

Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …

In the 12 years since the publication of the first Consensus Paper of the WFSBP on
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …

Transactive response DNA-binding protein 43 kD (TDP-43) is an aggregation-prone prion-
like domain-containing protein and component of pathological intracellular aggregates …

The neurodegenerative disorder Alzheimer's disease is characterised by the formation of β-
amyloid plaques and neurofibrillary tangles in the brain parenchyma, which cause synapse …

Since the beginning of the last decade, exosomes have been of increased interest in the
science community. Exosomes represent a new kind of long distance transfer of biological …