Innate humoral immune defences in mammals and insects: The same, with differences?

G Sheehan, A Garvey, M Croke, K Kavanagh - Virulence, 2018 - Taylor & Francis
The insect immune response demonstrates many similarities to the innate immune response
of mammals and a wide range of insects is now employed to assess the virulence of …

Immune priming: the secret weapon of the insect world

G Sheehan, G Farrell, K Kavanagh - Virulence, 2020 - Taylor & Francis
Insects are a highly successful group of animals that inhabit almost every habitat and
environment on Earth. Part of their success is due to a rapid and highly effective immune …

Recent Advances in the Use of Galleria mellonella Model to Study Immune Responses against Human Pathogens

TC Pereira, PP De Barros, LRO Fugisaki, RD Rossoni… - Journal of Fungi, 2018 - mdpi.com
The use of invertebrates for in vivo studies in microbiology is well established in the scientific
community. Larvae of Galleria mellonella are a widely used model for studying …

The Virtuous Galleria mellonella Model for Scientific Experimentation

I Serrano, C Verdial, L Tavares, M Oliveira - Antibiotics, 2023 - mdpi.com
The first research on the insect Galleria mellonella was published 85 years ago, and the
larva is now widely used as a model to study infections caused by bacterial and fungal …

Aspergillus fumigatus and aspergillosis: From basics to clinics

A Arastehfar, A Carvalho, J Houbraken… - Studies in …, 2021 - ingentaconnect.com
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …

[HTML][HTML] Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms

P Van Dijck, J Sjollema, BPA Cammue, K Lagrou… - Microbial Cell, 2018 - ncbi.nlm.nih.gov
Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …

Galleria mellonella as a model host for microbiological and toxin research

OL Champion, S Wagley, RW Titball - Virulence, 2016 - Taylor & Francis
Mammals are widely used by microbiologists as a model host species to study infectious
diseases of humans and domesticated livestock. These studies have been pivotal for our …

Galleria mellonella for the Evaluation of Antifungal Efficacy against Medically Important Fungi, a Narrative Review

S Jemel, J Guillot, K Kallel, F Botterel, E Dannaoui - Microorganisms, 2020 - mdpi.com
The treatment of invasive fungal infections remains challenging and the emergence of new
fungal pathogens as well as the development of resistance to the main antifungal drugs …

The Use of Galleria mellonella Larvae to Identify Novel Antimicrobial Agents against Fungal Species of Medical Interest

K Kavanagh, G Sheehan - Journal of Fungi, 2018 - mdpi.com
The immune system of insects and the innate immune response of mammals share many
similarities and, as a result, insects may be used to assess the virulence of fungal pathogens …

Aspergillus terreus species complex

C Lass-Flörl, AM Dietl, DP Kontoyiannis… - Clinical Microbiology …, 2021 - Am Soc Microbiol
Infections due to Aspergillus species are an acute threat to human health; members of the
Aspergillus section Fumigati are the most frequently occurring agents, but depending on the …