Dengue is widespread throughout the tropics and local spatial variation in dengue virus
transmission is strongly influenced by rainfall, temperature, urbanization and distribution of …

Recombinant proteins are gaining enormous importance these days due to their wide
application as biopharmaceutical products and proven safety record. Various recombinant …

Flaviviruses are enveloped single positive-stranded RNA viruses. The capsid (C), a
structural protein of flavivirus, is dimeric and alpha-helical, with several special structural …

Dengue viruses are emerging mosquito-borne pathogens belonging to Flaviviridae family
which are transmitted to humans via the bites of infected mosquitoes Aedes aegypti and …

This article aims to review the present status of anti-flavivirus subunit vaccines, both those at
the experimental stage and those already available for clinical use. Aspects regarding …

Despite the rapid development of vaccines against COVID-19, they have important
limitations, such as safety issues, the scope of their efficacy, and the induction of mucosal …

We developed a novel platform to express high levels of recombinant lipoproteins with
intrinsic adjuvant properties. Based on this technology, our group developed recombinant …

We describe the preclinical development of a dengue virus vaccine targeting the dengue
virus serotype 2 (DENV2) envelope domain III (EDIII). This study provides proof-of-principle …

A simple protocol was developed for the routine preparation of a kinetoplast DNA fraction
from trypanosomatids. The digestion of this DNA with selected restriction endonucleases …

Zika virus infection continues to be a global concern for human health due to the high-risk
association of the disease with neurological disorders and microcephaly in newborn …