Despite major strides in reducing cardiovascular disease (CVD) burden with modification of
classic CVD risk factors, significant residual risks remain. Recent discoveries that linked …

Cardiovascular disease (CVD) is the leading cause of death worldwide, especially in
developed countries, and atherosclerosis (AS) is the common pathological basis of many …

Trimethylamine N‐oxide (TMAO) is a biologically active molecule generated by the gut
microbiota. Accumulating evidences have indicated a close association between high …

It has been suggested that trimethylamine N‐oxide (TMAO) is associated with increased risk
of diabetes and cardiovascular disease (CVD) morbidity and mortality. However, it is not …

ABSTRACT Background Trimethylamine-N-oxide (TMAO) is a gut microbiota–derived
metabolite produced from dietary nutrients. Many studies have discovered that circulating …

Objective Bleeding after endoscopic submucosal dissection (ESD) for early gastric cancer
(EGC) is a frequent adverse event after ESD. We aimed to develop and externally validate a …

Trimethylamine (TMA) and its N-oxide (TMAO) are ubiquitous in prokaryote and eukaryote
organisms as well as in the environment, reflecting their fundamental importance in …

Wurtz et al. 6) conducted nuclear magnetic resonance (NMR) metabolomics to three
populationbased cohorts to identify biomarkers for incident CVD. The National Finnish …

Diet and nutrition have a substantial impact on the human microbiome, and interact with the
microbiome, especially gut microbiome, to modulate various diseases and health status …

ABSTRACT Background Trimethylamine N-oxide (TMAO), a diet-derived, gut microbial-host
cometabolite, has been linked to cardiometabolic diseases. However, the relations remain …