Transient receptor potential ankyrin 1 (TRPA1) is a polymodal ion channel sensitive to temperature and chemical stimuli. The importance of temperature and aversive chemical …
Y Wang, L Cao, CY Lee, T Matsuo, K Wu… - Nature …, 2018 - nature.com
Innate behaviors are genetically encoded, but their underlying molecular mechanisms remain largely unknown. Predator odor 2, 4, 5-trimethyl-3-thiazoline (TMT) and its potent …
GE Woodard, JA Rosado, H Li - Journal of Cellular and …, 2024 - Wiley Online Library
TRP channels, are non‐specific cationic channels that are involved in multiple physiological processes that include salivation, cellular secretions, memory extinction and consolidation …
S Tashiro, R Yamaguchi, S Ishikawa, T Sakurai… - Scientific reports, 2016 - nature.com
Various folk remedies employ certain odorous compounds with analgesic effects. In fact, linalool, a monoterpene alcohol found in lavender extracts, has been found to attenuate pain …
Transient receptor potential ankyrin 1 (TRPA1) is a polymodal excitatory ion channel found in sensory neurons of different organisms, ranging from worms to humans. Since its …
H Kashiwadani, Y Higa, M Sugimura… - Behavioral and Brain …, 2021 - Springer
We had recently reported that linalool odor exposure induced significant analgesic effects in mice and that the effects were disappeared in olfactory-deprived mice in which the olfactory …
RB Griggs, DE Laird, RR Donahue, W Fu… - Frontiers in …, 2017 - frontiersin.org
Methylglyoxal (MG) is a metabolite of glucose that may contribute to peripheral neuropathy and pain in diabetic patients. MG increases intracellular calcium in sensory neurons and …
T Kuwaki, N Takahashi - The Journal of Physiology, 2024 - Wiley Online Library
Transient receptor potential ankyrin 1 (TRPA1), a member of the TRP superfamily of cation channels, is broadly expressed in sensory neural pathways, including the trigeminal …
S Saito, CT Saito, M Nozawa, M Tominaga - Molecular Ecology, 2019 - Wiley Online Library
Ambient temperature fluctuations are detected via the thermosensory system which allows animals to seek preferable thermal conditions or escape from harmful temperatures …