Rheumatoid arthritis (RA) is a chronic autoimmune disease that can lead to joint damage
and even permanent disability, seriously affecting patients' quality of life. At present, the …

It is generally believed that immune activation can elicit pain through production of
inflammatory mediators that can activate nociceptive sensory neurons. Emerging evidence …

Background Dupilumab is an anti‐T2‐inflammatory biological registered for chronic
rhinosinusitis (CRS) with nasal polyps (CRSwNP), indicated by integrated CRS‐care …

Rheumatoid arthritis (RA) is a chronic autoimmune disease that has not been completely
treated for a long time. Therefore, effective therapy for RA is still urgently needed at present …

Non-HLA-directed regulatory autoantibodies (RABs) are known to target G-protein coupled
receptors (GPCRs) and thereby contribute to kidney transplant vasculopathy and failure …

Rheumatoid arthritis (RA) is a chronic inflammatory condition known for its irreversible
destructive impact on the joints. Chondrocytes play a pivotal role in the production and …

Objectives. This study evaluates the enduring efficacy and patient satisfaction of dupilumab
with interdose interval adjustments based on the Sino-Nasal Outcome Test (SNOT-22) in …

Background For Rheumatoid Arthritis (RA), a long-term chronic illness, it is essential to
identify and describe patient subtypes with comparable goal status and molecular …

Background: The rising costs of drugs are putting health care systems under pressure. We
report on the Bavarian Drug Agreement, which employs prescribing targets for preferred and …

Rheumatoid arthritis (RA) is characterized by high level of reactive oxygen species (ROS)
and proinflammatory cytokines, which facilitate the activation of the inflammatory signaling …