Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …

Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging
role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D) …

Acute physical activity leads to several changes in metabolic, cardiovascular, and immune
pathways. Although studies have examined selected changes in these pathways, the system …

Frailty is a common negative consequence of ageing. Sarcopenia, the syndrome of loss of
muscle mass, quality and strength, is more common in older adults and has been …

Purpose This review provides a current perspective on the mechanism of vitamin D on
skeletal muscle function with the emphasis on oxidative stress, muscle anabolic state and …

Maintenance of skeletal muscle mass is regulated by the balance between anabolic and
catabolic processes. Mammalian target of rapamycin (mTOR) is an evolutionarily conserved …

Atrophy occurs in specific muscles with inactivity (for example, during plaster cast
immobilization) or denervation (for example, in patients with spinal cord injuries). Muscle …

With the reignited push for manned spaceflight and the development of companies focused
on commercializing spaceflight, increased human ventures into space are inevitable …