Immune Microenvironment in Childhood Cancers: Characteristics and Therapeutic Challenges

AS Pathania - Cancers, 2024 - mdpi.com
Simple Summary The immune microenvironment surrounding a growing tumor is complex
and diverse. Understanding this complexity is crucial for predicting prognosis and response …

[HTML][HTML] Enhancing cancer immunotherapy: Nanotechnology-mediated immunotherapy overcoming immunosuppression

Y Chen, Q Zhou, Z Jia, N Cheng, S Zhang… - … Pharmaceutica Sinica B, 2024 - Elsevier
Immunotherapy is an important cancer treatment method that offers hope for curing cancer
patients. While immunotherapy has achieved initial success, a major obstacle to its …

Leveraging health care technology to improve health outcomes and reduce outcome disparities in AYA leukemia

JC Molina, S Rotz - Hematology, 2023 - ashpublications.org
Significant improvements have occurred for adolescent and young adult (AYA) B-cell acute
lymphoblastic leukemia (B-ALL) patients following the widespread adoption of “pediatric …

[HTML][HTML] Combination low-intensity chemotherapy plus inotuzumab ozogamicin, blinatumomab and rituximab for pediatric patients with relapsed/refractory B-cell acute …

A Gibson, C Nunez, L Robusto, B Kammerer… - …, 2024 - pmc.ncbi.nlm.nih.gov
The 5-year overall survival (OS) for pediatric patients with relapsed/refractory (R/R) B-cell
acute lymphoblastic leukemia (ALL) is< 50%. 1 Standard of care re-induction therapy is a …

Glycosylation as regulator of human B-cell leukaemias in bone marrow

N Heisterkamp - Frontiers in Hematology, 2023 - frontiersin.org
Leukemic B-cells are lodged in the bone marrow [BM], a complex organ composed of many
cell types and extracellular matrix. Determining how the reciprocal interactions between …

Targeting Serine Biosynthesis in Combination with Glutamine Modulation in Acute Myeloid Leukemia

KM Hameed - 2024 - search.proquest.com
Tumor development relies on metabolic reprogramming, offering therapeutic opportunities.
Glutamine (Gln) is an essential amino acid crucial for providing the necessary elements and …

[引用][C] Low‐dose venetoclax, bortezomib, inotuzumab, rituximab, and dexamethasone (LoVe‐BIRD) in a child with relapsed/refractory B‐cell acute lymphoblastic …

V Mohan, S Jain, R Naithani - Pediatric Blood & Cancer, 2024 - Wiley Online Library
Low‐dose venetoclax, bortezomib, inotuzumab, rituximab, and dexamethasone (LoVe‐
BIRD) in a child with relapsed/refractory B‐cell acute lymphoblastic leukemia with TP53 …