Stem cell factor (SCF) is a dimeric molecule that exerts its biological functions by binding to
and activating the receptor tyrosine kinase c-Kit. Activation of c-Kit leads to its …

Stem cell factor (SCF; also known as kit ligand, mast cell ultimate destinations during
development. Hematopoietic cells growth factor, or steel factor) is a hematopoietic cytokine …

Ongoing neurogenesis in the adult hippocampal dentate gyrus (DG) generates a substantial
population of young neurons. This phenomenon is present in all species examined thus far …

Dramatic pigmentation changes have evolved within most vertebrate groups, including fish
and humans. Here we use genetic crosses in sticklebacks to investigate the parallel origin of …

c-Kit is a receptor tyrosine kinase that binds stem cell factor (SCF). Structurally, c-Kit contains
five immunoglobulin-like domains extracellularly and a catalytic domain divided into two …

Stroke represents a severe medical condition that causes stroke survivors to suffer from long-
term and even lifelong disability. Over the past several decades, a vast majority of stroke …

Neural stem cells (NSCs) possess high potencies of self-renewal and neuronal
differentiation. We explored here whether transplantation of human NSCs cloned by v-myc …

Cerebral ischemia stimulates neurogenesis in proliferative zones of the rodent forebrain. To
identify the signaling factors involved, cerebral cortical cultures prepared from embryonic …

The receptors for platelet-derived growth factor (PDGF) and stem cell factor (SCF) are
members of the type III class of PTK receptors, which are characterized by five Ig-like …

Kit‐ligand (Kitl) also known as steel factor, stem cell factor and mast cell growth factor plays
a crucial role in the development and maintenance of the melanocyte lineage in adult skin …