Genetic engineering of Trichoderma reesei cellulases and their production

IS Druzhinina, CP Kubicek - Microbial biotechnology, 2017 - Wiley Online Library
Lignocellulosic biomass, which mainly consists of cellulose, hemicellulose and lignin, is the
most abundant renewable source for production of biofuel and biorefinery products. The …

The influence of feedstock characteristics on enzyme production in Trichoderma reesei: a review on productivity, gene regulation and secretion profiles

V Novy, F Nielsen, B Seiboth, B Nidetzky - Biotechnology for biofuels, 2019 - Springer
Biorefineries, designed for the production of lignocellulose-based chemicals and fuels, are
receiving increasing attention from the public, governments, and industries. A major obstacle …

Building a Versatile Protein Production Platform Using Engineered Trichoderma reesei

S Chai, Z Zhu, E Tian, M Xiao, Y Wang… - ACS Synthetic …, 2021 - ACS Publications
Trichoderma reesei has an extremely high capacity for synthesizing and secreting proteins,
thus exhibiting promise as an expression platform for heterologous proteins. However, T …

Novel genetic tools that enable highly pure protein production in Trichoderma reesei

A Rantasalo, M Vitikainen, T Paasikallio, J Jäntti… - Scientific reports, 2019 - nature.com
Trichoderma reesei is an established protein production host with high natural capacity to
secrete enzymes. The lack of efficient genome engineering approaches and absence of …

Regulation of plant cell wall degradation by light in Trichoderma

M Schmoll - Fungal Biology and Biotechnology, 2018 - Springer
Trichoderma reesei (syn. Hypocrea jecorina) is the model organism for industrial production
of plant cell wall degradating enzymes. The integration of light and nutrient signals for …

A universal gene expression system for fungi

A Rantasalo, CP Landowski, J Kuivanen… - Nucleic acids …, 2018 - academic.oup.com
Biotechnological production of fuels, chemicals and proteins is dependent on efficient
production systems, typically genetically engineered microorganisms. New genome editing …

A comparison of Monte Carlo sampling methods for metabolic network models

S Fallahi, HJ Skaug, G Alendal - Plos one, 2020 - journals.plos.org
Reaction rates (fluxes) in a metabolic network can be analyzed using constraint-based
modeling which imposes a steady state assumption on the system. In a deterministic …

Identification of a novel repressor encoded by the putative gene ctf1 for cellulase biosynthesis in Trichoderma reesei through artificial zinc finger engineering

QS Meng, F Zhang, CG Liu, XQ Zhao… - Biotechnology and …, 2020 - Wiley Online Library
Strains from Trichoderma reesei have been used for cellulase production with a long history.
It has been well known that cellulase biosynthesis by the fungal species is controlled …

Inducer-free recombinant protein production in Trichoderma reesei: secretory production of endogenous enzymes and heterologous nanobodies using glucose as …

T Arai, M Wada, H Nishiguchi, Y Takimura, J Ishii - Microbial Cell Factories, 2023 - Springer
Abstract Background The filamentous fungus Trichoderma reesei has been used as a host
organism for the production of lignocellulosic biomass-degrading enzymes. Although this …

Transcriptome-wide analysis of a superior xylan degrading isolate Penicillium oxalicum 5–18 revealed active lignocellulosic degrading genes

S Hu, P Han, BT Wang, L Jin, HH Ruan, FJ Jin - Archives of Microbiology, 2024 - Springer
Lignocellulose biomass raw materials have a high value in energy conversion. Recently,
there has been growing interest in using microorganisms to secret a series of enzymes for …