Regulatory T (Treg) cells represent a distinct lineage of cells of the adaptive immune system
indispensable for forestalling fatal autoimmune and inflammatory pathologies. The role of …

Involvement of TIGIT in Natural Killer Cell Exhaustion and I... : Hepatology Involvement of
TIGIT in Natural Killer Cell Exhaustion and Immune Escape in Patients and Mouse Model With …

Abstract Fibrinogen-like protein 2 (FGL2), a member of the fibrinogen family, exists as a
membrane-bound protein with immune-associated coagulation activity and a soluble form …

Background and Aims Alveolar echinococcosis (AE) is a lethal helminthic liver disease
caused by persistent infection with Echinococcus multilocularis. Although more attention has …

Immunoglobulin E (IgE) responses are a central feature of allergic disease. Using a well-
established food-allergy model in mice, we show that two sensitizations with cognate B cell …

Introduction Ulcerative colitis [UC] is a chronic disease with rising incidence and unclear
aetiology. Deep molecular phenotyping by multiomics analyses may provide novel insights …

The initial idea of a distinct group of T-cells responsible for suppressing immune responses
was first postulated half a century ago. However, it is only in the last three decades that we …

The perinatal period is a critical time window in establishing T cell tolerance. Regulatory T
cells (Tregs) made during the first 2 wk of life are key drivers of perinatal tolerance induction …

Background and Aims NAFLD is the most common hepatic pathology in western countries
and no treatment is currently available. NAFLD is characterized by the aberrant …

T follicular regulatory (TFR) cells are found in the germinal center (GC) response and, along
with T follicular helper (TFH) cells, help to control the development of high-affinity antibodies …