New pyrazole and pyrazoline derivatives have been synthesized and their ability to inhibit
ovine COX-1/COX-2 isozymes was evaluated using in vitro cyclooxygenase (COX) inhibition …

A group of 30 cyclic imides (1–10a-c) was designed for evaluation as a selective COX-2
inhibitor and investigated in vivo for anti-inflammatory and analgesic activities. Compounds …

Condensation of 9-chloro-2, 4-(un) substituted acridines (1a–c) with various amines (2a–e)
and 9-isothiocyanato-2, 4-(un) substituted acridines (4a, b) with different amines (2a, b, d, e) …

Cyclic imides are commonly encountered structural motifs in natural and synthetic molecules
with remarkable pharmacological properties. They are also used widely for further …

A group of cyclic imides (1–13) was designed for evaluation as selective COX-2 inhibitors
and investigated in vivo for their anti-inflammatory activities using carrageenan-induced rat …

A highly enantioselective [3+ 2] annulation of MBH carbonates and maleimides catalyzed by
chiral phosphines has been developed. In the presence of 5 mol% of l-Thr-l-Val-derived …

Heterocyclic benzimidazole derivatives 3a–h, 5a–c and 7a–d have been synthesized by
condensation of succinic acid (1) homophthalic acid (4) and 2, 3-pyrazinedicarboxlic acid (6) …

Alzheimer's disease (AD) is drawing scientists' consideration, being one of the gravest
diseases mankind will have to battle against in the near future. The number of people with …

Certain new halogenated cyclic-imides related to N-substituted phthalimide moiety were
synthesized. Spacers of one or two carbon atom distances were inserted to connect the N …

A group of cyclic imides (1–10) was designed for evaluation as a selective COX-2 inhibitors
and investigated in vivo for their anti-inflammatory activity. Compounds 6a, 6b, 8a, 8b, 9a …