Serotonin and psychostimulant addiction: focus on 5-HT1A-receptors
CP Müller, RJ Carey, JP Huston, MADS Silva - Progress in neurobiology, 2007 - Elsevier
Serotonin1A-receptors (5-HT1A-Rs) are important components of the 5-HT system in the
brain. As somatodendritic autoreceptors they control the activity of 5-HT neurons, and, as …
brain. As somatodendritic autoreceptors they control the activity of 5-HT neurons, and, as …
Ecstasy (MDMA): a review of its possible persistent psychological effects
MJ Morgan - Psychopharmacology, 2000 - Springer
Rationale: Recreational use of" ecstasy"(3, 4-methylenedioxymethamphetamine; MDMA)
has become increasingly widespread. Until recently, however, little was known about the …
has become increasingly widespread. Until recently, however, little was known about the …
Memory deficits associated with recreational use of “ecstasy”(MDMA)
MJ Morgan - Psychopharmacology, 1999 - Springer
Evidence from both animal, and human, studies suggests that repeated administration of 3,
4-methylenedioxymethamphetamine (MDMA;“ecstasy”) produces lasting decreases in …
4-methylenedioxymethamphetamine (MDMA;“ecstasy”) produces lasting decreases in …
Neuropsychological evidence of a relatively selective profile of temporal dysfunction in drug-free MDMA (" ecstasy") polydrug users
Heading Abstract Rationale. Experimental evidence has shown that 3, 4-
methylenedioxymethamphetamine (MDMA," ecstasy") can act as a serotonergic neurotoxin …
methylenedioxymethamphetamine (MDMA," ecstasy") can act as a serotonergic neurotoxin …
Memory impairment in abstinent MDMA (“ecstasy”) users: a longitudinal investigation
KK Zakzanis, DA Young - Neurology, 2001 - AAN Enterprises
To examine the neurotoxic potential of continued MDMA (“Ecstasy”) use in humans and its
functional consequences over the course of 1 year, 15 MDMA users participated in a …
functional consequences over the course of 1 year, 15 MDMA users participated in a …
A neurotoxic regimen of MDMA suppresses behavioral, thermal and neurochemical responses to subsequent MDMA administration
M Shankaran, GA Gudelsky - Psychopharmacology, 1999 - Springer
Abstract Rationale: 3, 4-Methylenedioxymethamphetamine (MDMA) produces a long-term
depletion of serotonin (5-HT) in the rat brain; this depletion may have some functional …
depletion of serotonin (5-HT) in the rat brain; this depletion may have some functional …
Serotonin 5‐HT1A receptor expression is selectively enhanced in the striosomal compartment of chronic parkinsonian monkeys
D Frechilla, A Cobreros, L Saldise, R Moratalla… - Synapse, 2001 - Wiley Online Library
Cynomolgus monkeys (Macaca fascicularis) were chronically treated with the dopaminergic
neurotoxin 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine (MPTP) until stable …
neurotoxin 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine (MPTP) until stable …
Drug withdrawal-induced depression: serotonergic and plasticity changes in animal models
This review discusses recent research of mood disorders associated with the cessation of
psychoactive substances, with an emphasis on preclinical studies that have been published …
psychoactive substances, with an emphasis on preclinical studies that have been published …
Serotonin 5-HT1A receptor mRNA expression in dorsal hippocampus and raphe nuclei after gonadal hormone manipulation in female rats
V Birzniece, IM Johansson, MD Wang, JR Seckl… - …, 2001 - karger.com
Female ovarian steroids influence mood and cognition, an effect presumably mediated by
the serotonergic system. A key receptor in this interplay may be the 5-HT 1A receptor …
the serotonergic system. A key receptor in this interplay may be the 5-HT 1A receptor …
MDMA (Ecstasy') enhances 5-HT1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion
N Aguirre, S Ballaz, B Lasheras, J Del Rıo - European journal of …, 1998 - Elsevier
One week after a single administration of 3, 4-methylenedioxymethamphetamine (MDMA·
HCl, 30 mg/kg ip), 5-HT1A receptor density was significantly increased by approximately 25 …
HCl, 30 mg/kg ip), 5-HT1A receptor density was significantly increased by approximately 25 …