Background Genotype imputation can help reduce genotyping costs particularly for implementation of genomic selection. In applications entailing large populations, recovering …
We wrote this book to fill the gap between textbooks of quantitative genetic theory and software manuals that provide details on analytical methods but little context or perspective …
In livestock, many studies have reported the results of imputation to 50k single nucleotide polymorphism (SNP) genotypes for animals that are genotyped with low-density SNP …
Genomic evaluation methods assume that the reference population is genotyped and phenotyped. This is most often false and the generation of pseudo-phenotypes is uncertain …
L Ma, JR O'Connell, PM VanRaden, B Shen… - PLoS …, 2015 - journals.plos.org
Meiotic recombination is an essential biological process that generates genetic diversity and ensures proper segregation of chromosomes during meiosis. From a large USDA dairy …
Background Millions of genetic variants have been identified by population-scale sequencing projects, but subsets of these variants are needed for routine genomic …
Background The development of next-generation sequencing technologies (NGS) has made the use of whole-genome sequence data for routine genetic evaluations possible, which has …
Many computations with SNP data including genomic evaluation, parameter estimation, and genome-wide association studies use an inverse of the genomic relationship matrix. The …
JL Smith, ML Wilson, SM Nilson, TN Rowan… - BMC genomics, 2022 - Springer
Background Genotypic information produced from single nucleotide polymorphism (SNP) arrays has routinely been used to identify genomic regions associated with complex traits in …