[HTML][HTML] Microbiome-based interventions to modulate gut ecology and the immune system

TCA Hitch, LJ Hall, SK Walsh, GE Leventhal, E Slack… - Mucosal …, 2022 - Elsevier
The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …

Gut microbiome: a biomedical revolution

MC Collado, S Devkota, TS Ghosh - Nature Reviews Gastroenterology …, 2024 - nature.com
To mark the twentieth anniversary of Nature Reviews Gastroenterology & Hepatology, we
asked three experts to comment on how the gut microbiome has transformed our …

Obesity and diet independently affect maternal immunity, maternal gut microbiota and pregnancy outcome in mice

L Wekema, S Schoenmakers, N Schenkelaars… - Frontiers in …, 2024 - frontiersin.org
Introduction Maternal obesity poses risks for both mother and offspring during pregnancy,
with underlying mechanisms remaining largely unexplored. Obesity is associated with …

Shaping microbiota during the first 1000 days of life

A Samarra, E Flores, M Bernabeu… - Probiotics and Child …, 2024 - Springer
Given that the host-microbe interaction is shaped by the immune system response, it is
important to understand the key immune system-microbiota relationship during the period …

Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring

S Wang, Y Liu, WH Tam, JYL Ching, W Xu, S Yan… - Cell Host & Microbe, 2024 - cell.com
The impact of gestational diabetes mellitus (GDM) on maternal or infant microbiome
trajectory remains poorly understood. Utilizing large-scale longitudinal fecal samples from …

Placental adaptations supporting fetal growth during normal and adverse gestational environments

AN Sferruzzi‐Perri, J Lopez‐Tello… - Experimental …, 2023 - Wiley Online Library
The placenta is vital for mammalian development and a key determinant of life‐long health.
It is the interface between the mother and fetus and is responsible for transporting the …

From gut to placenta: understanding how the maternal microbiome models life-long conditions

J Ruiz-Triviño, D Álvarez, ÁP Cadavid J… - Frontiers in …, 2023 - frontiersin.org
The microbiome-defined as the microbiota (bacteria, archaea, lower and higher eukaryotes),
their genomes, and the surrounding environmental conditions-has a well-described range of …

Alterations in the gut microbiome and metabolisms in pregnancies with fetal growth restriction

Z Tao, Y Chen, F He, J Tang, L Zhan, H Hu… - Microbiology …, 2023 - Am Soc Microbiol
Fetuses diagnosed with fetal growth restriction (FGR) are at an elevated risk of stillbirth and
adulthood morbidity. Gut dysbiosis has emerged as one of the impacts of placental …

Gut microbiota contributes to bisphenol A-induced maternal intestinal and placental apoptosis, oxidative stress, and fetal growth restriction in pregnant ewe model by …

H Zhang, X Zha, B Zhang, Y Zheng, M Elsabagh… - Microbiome, 2024 - Springer
Abstract Background Bisphenol A (BPA) is an environmental contaminant with endocrine-
disrupting properties that induce fetal growth restriction (FGR). Previous studies on pregnant …

Heat stress-induced fetal intrauterine growth restriction is associated with elevated LPS levels along the maternal intestine–placenta–fetus Axis in pregnant mice

X Zheng, W Ma, Y Wang, C Wu, J Wang… - Journal of Agricultural …, 2023 - ACS Publications
The exacerbation of the greenhouse effect has made heat stress (HS) an important risk
factor for the occurrence of intrauterine growth restriction (IUGR). The experiment aims to …