Melanin production from different types of phenoloxidases (POs) confers immunity from a
variety of pathogens ranging from viruses and microorganisms to parasites. The arthropod …

Mosquito-transmitted diseases, including malaria and dengue, are a major threat to human
health around the globe, affecting millions each year. A diverse array of next-generation …

Gene drives hold promise for the genetic control of malaria vectors. The development of
vector population modification strategies hinges on the availability of effector mechanisms …

Malaria is one of the deadliest diseases. Because of the ineffectiveness of current malaria-
control methods, several novel mosquito vector-based control strategies have been …

Malaria parasites are less vulnerable to mosquito immune responses once ookinetes
transform into oocysts, facilitating parasite development in the mosquito. However, the …

Gene drives for mosquito population replacement are promising tools for malaria control.
However, there is currently no clear pathway for safely testing such tools in endemic …

Mosquito immunity is composed of both cellular and humoral factors that provide protection
from invading pathogens. Immune cells known as hemocytes, have been intricately …

Mosquito blood cells are immune cells that help control infection by vector-borne pathogens.
Despite their importance, little is known about mosquito blood cell biology beyond …

Background Gene drives are a genetic engineering method where a suite of genes is
inherited at higher than Mendelian rates and has been proposed as a promising new vector …

Mosquito transgenesis and gene-drive technologies provide the basis for developing
promising new tools for vector-borne disease prevention by either suppressing wild …