Balancing selection and heterogeneity across the classical human leukocyte antigen loci: a meta-analytic review of 497 population studies

OD Solberg, SJ Mack, AK Lancaster, RM Single… - Human immunology, 2008 - Elsevier
This paper presents a meta-analysis of high-resolution human leukocyte antigen (HLA)
allele frequency data describing 497 population samples. Most of the datasets were …

HLA class I (A, B, C) and class II (DRB1, DQA1, DQB1, DPB1) alleles and haplotypes in the Han from southern China

E Trachtenberg, M Vinson, E Hayes, YM Hsu… - Tissue …, 2007 - Wiley Online Library
In this study, polymerase chain reaction‐sequence‐specific oligonucleotide prode (SSOP)
typing results for the human leukocyte antigen (HLA) class I (A, B, and C) and class II (DRB1 …

[HTML][HTML] Natural Selection on HLA-DPB1 Amino Acids Operates Primarily on DP Serologic Categories

RM Single, SJ Mack, OD Solberg, G Thomson… - Human Immunology, 2024 - Elsevier
The DPB1 locus is notable among the classical HLA loci in that allele frequencies at this
locus are consistent with genetic drift, whereas the frequencies of specific DPβ amino acids …

[HTML][HTML] Population Genetic Dissection of HLA-DPB1 Amino Acid Polymorphism to Infer Selection

SJ Mack, RM Single, OD Solberg, G Thomson… - Human Immunology, 2024 - Elsevier
Although allele frequency data for most HLA loci provide strong evidence for balancing
selection at the allele level, the DPB1 locus is a notable exception, with allele frequencies …

The association of HLA-DRB1 alleles with antineutrophil cytoplasmic antibody-associated systemic vasculitis in Chinese patients

H Luo, M Chen, R Yang, PC Xu, MH Zhao - Human immunology, 2011 - Elsevier
Antineutrophil cytoplasmic antibody (ANCA)–associated systemic vasculitis (AASV) is a
group of autoimmune diseases. The human leukocyte antigen (HLA) system is devoted to …

The genetic relationship among Iranian ethnic groups: an anthropological view based on HLA class II gene polymorphism

S Farjadian, M Ota, H Inoko, A Ghaderi - Molecular biology reports, 2009 - Springer
Highly polymorphic human leukocyte antigen (HLA) genes are considered as useful
markers by molecular anthropologists to determine genetic relationship among populations …

Distribution of human leucocyte antigen‐A,‐B and‐DR alleles and haplotypes at high resolution in the population from Jiangsu province of China

P Qin Qin, F Su, W Xiao Yan, Z Xing… - International Journal …, 2011 - Wiley Online Library
The frequencies of human leucocyte antigen (HLA)‐A,‐B and‐DRB1 alleles and haplotypes
were statistically analysed among 3238 donors from Chinese Marrow Donor Program …

HLA class II similarities in Iranian Kurds and Azeris

S Farjadian, A Ghaderi - International journal of …, 2007 - Wiley Online Library
The genetic relationship between Kurds and Azeris of Iran was investigated based on
human leukocyte antigen (HLA) class II profiles. HLA typing was performed using …

HLA-DQA1* 03: 02/DQB1* 03: 03: 02 is strongly associated with susceptibility to childhood-onset ocular myasthenia gravis in Southern Han Chinese

WH Zhu, JH Lu, J Lin, JY Xi, J Lu, SS Luo… - Journal of …, 2012 - Elsevier
OBJECTIVE: Our aim was to investigate the correlation between onset age, clinical features
and HLA-DQA1/DQB1 genetic variability in myasthenia gravis (MG) patients in Southern …

Human leukocyte antigen class I and class II allele frequencies and HIV-1 infection associations in a Chinese cohort

S Li, H Jiao, X Yu, AJ Strong, Y Shao… - JAIDS Journal of …, 2007 - journals.lww.com
China has one of the most rapidly spreading HIV-1 epidemics. To develop a vaccine
targeted to specific human leukocyte antigen (HLA) epitopes in this population, allele …